【摘要】 目的 探讨老年2型糖尿病（type2diabetesmellitus,T2DM）患者自然功能牙数量及口腔修复情况对营养风险的影响。方法 选取2023年9月至2024年3月在南京医科大学第一附属医院内分泌科住院的老年T2DM患者296例作为研究对象，调查患者自然功能牙数量及口腔修复情况，采用老年营养风险指数（geriatric nutritional risk index,GNRI）评估患者营养状态，采用Spearman相关性分析和多元线性回归分析老年T2DM患者GNRI的影响因素。结果 296例患者中，251例（84.8%）患者存在牙齿缺失的情况，患者自然功能牙数为24.0(15.3,27.0)颗。Spearman相关性分析显示，患者自然功能牙数量与GNRI呈正相关（r=0.156,P=0.007）。口腔完全修复者73例（24.66%）、不完全修复者64例（21.62%）、异常修复者10例（3.38%）、完全未修复者104例（35.14%）、无需修复者45例（15.20%）；单因素方差分析显示，不同口腔修复行为患者GNRI比较，存在显著差异（F=4.907,P=0.001）。多元线性回归分析显示，口腔不完全修复（t=-2.089,P=0.038）和完全未修复（t=-2.416,P=0.016）是患者GNRI的独立危险因素。结论 老年T2DM患者牙齿脱落情况普遍存在，自然功能牙数量及不同口腔修复行为是老年T2DM患者营养风险的危险因素。更多还原

【Abstract】 Objective To investigate the effects of the Number of Natural Functional Teeth and Oral Rehabilitation Status on Nutritional Risk in Elderly Patients with type 2 Diabetes Mellitus(T2DM). Methods A total of 296 elderly patients with T2DM who were hospitalized in the Department of Endocrinology of the first affiliated hospital with Nanjing medical university from September 2023 to March 2024 were recruited as research participants. The number of natural functional teeth and oral restoration conditions among these patients were systematically assessed. The geriatric nutritional risk index(GNRI) was used to assess the nutritional status of the patients. The influencing factors of GNRI in elderly patients with T2DM were analyzed by Spearman correlation analysis and multiple linear regression analysis. Results Among the 296 patients, 251 cases(84.8%) had tooth loss, and the number of natural functional teeth of the patients was 24.0(15.3, 27.0). Spearman correlation analysis revealed a positive correlation between the number of natural functional teeth and the GNRI(r=0.156, P=0.007). Of the total, 73 patients(24.66%) had complete oral restoration, 64(21.62%) had incomplete restoration, 10(3.38%) had abnormal restoration, 104(35.14%) had no restoration, and 45(15.20%) did not require restoration. One-way analysis of variance showed that there were significant differences in GNRI among patients with different dental restoration behaviors(F=4.907, P=0.001). Multiple linear regression analysis showed that incomplete dental repair(t=-2.089, P=0.038) and completely unrepaired(t=-2.416, P=0.016) were independent risk factors for GNRI. Conclusion Tooth loss is common in elderly patients with T2DM, and the number of functional natural teeth and different oral restoration behaviors were risk factors for nutritional risk.更多还原