【摘要】 目的 分析儿童肿瘤溶解综合征(TLS)并发急性肾损伤(AKI)的危险因素。方法 回顾性分析2015年10月—2023年12月就诊于湖南省儿童医院TLS患儿的临床资料，将其分为AKI组(n=23)以及非AKI组(n=23),对患儿的临床资料进行统计学分析，明确TLS患儿发生AKI的危险因素。结果 46例TLS患儿，AKI发生率为50%,血磷水平为TLS患儿发生AKI的独立危险因素，且血磷水平增高与AKI的严重程度相关。结论 血磷水平为TLS患儿发生AKI的独立危险因素，其变化程度可能预测严重肾脏功能损害的发生。更多还原

【Abstract】 Objective To analyze the risk factors analysis of tumor lysis syndrome in children with acute renal injury. Methods A retrospective study was conducted on 46 children with Tumor lysis syndrome admitted to our hospital from January 2015 to December 2023, they divided into AKI group(n=23) and non-AKI group(n=23). The general data and clinical data were analyzed. Results The incidence of AKI in 46 children with TLS was 50%. Blood phosphorus level was an independent risk factor for AKI in children with TLS, and the increase of blood phosphorus level was related to the severity of AKI. Conclusions As an independent risk factor of AKI in children with TLS, and its change degree can probably be used as a predictive index for severe renal function damage.更多还原