【摘要】 目的 了解上海市0～12月龄儿童照护者对儿童呼吸道合胞病毒(Respiratory syncytial virus, RSV)感染防治知识、态度和行为(Knowledge, attitude and practice, KAP)现状及其影响因素。方法 于2024年12月采用方便抽样方法在上海市7家RSV单克隆抗体试点使用单位、11家社区卫生服务中心和1家私立医院选择0～12月龄儿童照护者开展RSV感染防治KAP问卷调查，分析KAP正确/正向比例、平均得分(满分为12分)及其影响因素。结果 在1 732例调查对象中，RSV感染防治KAP各条目正确/正向比例在11.55%～84.70%之间，KAP得分中位数(四分位数间距)为7(4～9)分。多重线性回归分析显示，照护者文化程度、职业和儿童出生体重是KAP得分的影响因素，大专、本科、硕士及以上文化程度者KAP得分高于高中/中专及以下文化程度者[β(95%CI):107.80(18.66～196.94)、239.83(163.69～315.97)、190.62(107.61～273.62)],医疗卫生相关行业者高于非医疗卫生相关行业者[β(95%CI):272.36(207.30～337.43)],出生体重>5.0 kg、2.5～5.0 kg儿童照护者低于出生体重<2.5 kg儿童照护者[β(95%CI):-156.83(-258.03～-55.64)、-135.60(-224.86～-46.34)]。结论 上海市0～12月龄儿童照护者对儿童RSV感染防治KAP总体水平较低；需加强RSV感染防治健康教育，促进儿童RSV单克隆抗体使用。更多还原

【Abstract】 Objective To assess knowledge, attitudes, and practices(KAP) for prevention and control of respiratory syncytial virus(RSV) infection and factors influencing KAPs among caregivers of 0-12-month-old children.Methods We selected convenience samples of caregivers of 0-12-month-old children in 7 hospitals that had pilot use of RSV monoclonal antibody, 11 community health service centers, and 1 private hospital in Shanghai in December 2024. We conducted a questionnaire-based survey of KAP on RSV infection prevention and control to determine proportions of correct/positive KAP answers, average scores(maximum, 12) and factors influencing KAP.Results Among 1 732 caregivers, proportions of correct/positive response to KAP items ranged from 11.55% to 84.70%, with a median KAP score(interquartile range) of 7(4-9) points. Multiple linear regression analyses showed that education level, caregiver occupation, and infant birth weight influenced KAPs. Score were higher among caregivers with a college, bachelor′s, and master′s degree or above education level than those with a high school education or below [β(95% CI): 107.80(18.66 to 196.94), 239.83(163.69 to 315.97), and 190.62(107.61 to 273.62)]. Scores were higher among caregivers in healthcare sectors than those in non-healthcare sectors [β(95% CI): 272.36(207.30 to 337.43)], and lower among caregivers of infants with a birth weight of >5.0 kg and 2.5-5.0 kg compared with infants with a birth weight of <2.5 kg [β(95% CI):-156.83(-258.03 to-55.64), and-135.60(-224.86 to-46.34)].Conclusions Overall RSV infection prevention and control KAP levels were low among caregivers of 0-12-month-old children in Shanghai. It is necessary to strengthen health education on RSV infection prevention and control and promote the use of RSV monoclonal antibodies for children.更多还原