【摘要】 自主神经系统功能障碍是帕金森病（PD）最常见的非运动症状之一，而直立位低血压（OH）是自主神经功能障碍常见的特征之一。OH和认知障碍在PD非运动症状中最为常见，可贯穿疾病全程。这两种非运动症状之间是否具有相关性，目前尚不清楚。目前PD-OH与认知功能障碍关系在国外已有较多的研究，而国内类似研究极少。因此，本文从帕金森病认知障碍及直立位低血压二者之间关系进行概述，为帕金森病认知障碍的发病机制、治疗及预防提供参考，为PD认知障碍带来新的治疗思路。更多还原

【Abstract】 Autonomic nervous system dysfunction is one of the most common non-motor symptoms of Parkinson disease(PD), and orthostatic hypotension(OH) is one of the common features of autonomic nervous system dysfunction. OH and cognitive impairment are the most common non-motor symptoms of PD and can run through the whole course of the disease, and it remains unclear whether there is an association between these two non-motor symptoms. At present, a large number of studies have been conducted on the association between PD-OH and cognitive impairment abroad, but there are few similar studies in China. Therefore, this article summarizes the association between cognitive impairment and OH in PD, in order to provide a reference for the pathogenesis, treatment, and prevention of cognitive impairment in PD and brings new ideas for the treatment of cognitive impairment in PD.更多还原