【摘要】 目的 从疾病临床特征及患者社会学特征多维变量探讨影响嗓音矫治治疗良性嗓音障碍性疾病效果的相关因素。方法 回顾分析2020年1月—2023年11月就诊于西安交通大学第二附属医院耳鼻咽喉头颈外科嗓音门诊并接受嗓音矫治治疗的良性嗓音障碍性疾病患者262例。将以上患者按照随访结果分为有效组与无效组，应用SPSS 25.0统计分析患者疾病临床特征、社会学特征及治疗次数对治疗效果的影响。结果 262例患者接受嗓音矫治治疗总有效率为88.17%。单因素分析显示：两组患者在年龄、性别、职业类型、文化程度、家庭住址、城乡分布、年收入层次及吸烟、饮酒史方面无统计学差异；多因素分析表明年龄、疾病类型、治疗次数、发音障碍严重程度指数(DSI)、嗓音障碍指数量表-10(VHI-10)评分及听主观总嘶哑度(G)、粗糙度(R)、气息度(B)、无力度(A)、紧张度(S)评分中的B评分与S评分在两组患者中具有统计学差异。结论 嗓音矫治治疗有效的患者具有病史时间更短、VHI-10评分更高的特点；功能性嗓音障碍性疾病嗓音矫治治疗效果优于器质性疾病；依从性高、接受嗓音矫治治疗次数越多的患者具有更好的疗效；高龄及高B、S评分是嗓音矫治治疗效果的不利因素；高DSI评分是嗓音矫治治疗效果的有利因素。更多还原

【Abstract】 Objective To investigate the factors affecting the effect of voice correction therapy for benign voice disorders from the multidimensional variables of clinical characteristics and the patients’ sociological characteristics.Methods A retrospective analysis was conducted on the clinical data of 262 patients with benign voice disorders who received voice correction therapy at the Voice Clinic of the Department of Otolaryngology Head and Neck Surgery at the Second Affiliated Hospital of Xi’an Jiaotong University from January, 2020 to November, 2023. The above-mentioned patients were divided into the effective group and the ineffective group according to the follow-up results. Statistical analysis using SPSS 25.0 software was conducted to determine the impacts of clinical characteristics of the disease, the sociological characteristics of the patients, and the number of treatments on the treatment outcome.Results The total effective rate of 262 patients receiving voice correction therapy was 88.17%. Univariate analysis revealed no statistically significant differences between the two groups in terms of age, gender, occupation, education level, residential address, urban-rural distribution, annual income level, and history of smoking and alcohol consumption.Multivariate analysis indicated that the age, type of disease, number of treatments, dysphonia severtity index, voice handicap index-10 score, B score and S score in the grade, roughness, breathiness, asthenia, strain assessment showed statistically significant differences between the two groups.Conclusions Patients who respond effectively to voice correction therapy tend to have a shorter history and higher voice handicap index-10 scores. The voice correction therapy for functional voice disorders is more effective than that for organic diseases. Patients with higher compliance and more times of receiving voice correction therapy have better therapeutic effects. Advanced age and high B and S scores are unfavorable factors for the outcome of voice correction, while a high dysphonia severtity index score is a favorable factor.更多还原