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中药饮片等级量化评价方法研究进展与趋势

Research progress and trend of quantitative evaluation methods of traditional Chinese medicine decoction pieces

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【作者】 钱淼华张晓勇朱斐梁卫青汪涛向文史星雲冷华南贾良权姚冲

【Author】 QIAN Miaohua;ZHANG Xiaoyong;ZHU Fei;LIANG Weiqing;WANG Tao;XIANG Wen;SHI Xingyun;LENG Huanan;JIA Liangquan;YAO Chong;Affiliated Central Hospital of Huzhou University (Huzhou Central Hospital);Institute of Basic Medicine and Cancer,Chinese Academy of Sciences;Zhejiang Provincial Center for Medicine Science Technology & Education Development;Zhejiang Academy of Traditional Chinese Medicine;Nanjing Agricultural University;Huzhou Institute for Food and Drug Control;Huzhou Academy of Agricultural Science;Huzhou Research Institute of Forestry;School of Information Engineering,Huzhou University;

【通讯作者】 姚冲;

【机构】 湖州师范学院附属中心医院(湖州市中心医院)中国科学院基础医学与肿瘤研究所浙江省医学科技教育发展中心浙江省中医药研究院南京农业大学湖州市食品药品检验研究院湖州市农业科学研究院湖州市国有林场湖州师范学院信息工程学院

【摘要】 中药饮片的质量评价在中药饮片的市场交易与临床应用中具有重要的作用,其质量直接影响到其临床的作用。为了确保中药饮片的安全性和有效性,对其进行质量控制方法的探索尤为重要。中药饮片的质量与其理化性质密切相关,对其进行定性和定量研究是目前中药饮片质量控制的常用手段。而中药饮片的成分复杂,对其进行质量判定方法的准确性和全面性仍需进一步完善。在前有研究成果的基础上,通过对近年来中药饮片等级量化评价方法进行系统的整理与总结,提出了一种基于“形质效”理论的中药等级综合评价方法。该方法结合了中药的外观形态、理化性质和药效等多维度因素,能够更全面地评估中药饮片的综合质量。为中药饮片质量评价体系的建立提供参考,同时为后续研究中药饮片的评价方法的研究提供理论基础。

【Abstract】 The quality evaluation of traditional Chinese medicine(TCM) decoction pieces plays a crucial role in both market transactions and clinical applications. The quality of TCM decoction pieces directly affects their clinical efficacy. In order to ensure the safety and effectiveness of these decoction pieces, it is vital to explore methods for quality control. The quality of TCM decoction pieces is closely related to their physicochemical properties, and qualitative and quantitative studies are common approaches for quality control. However, due to the complex composition of these decoction pieces, the accuracy and comprehensiveness of quality assessment methods still need to be further improved. Building on previous research, the article systematically reviews and summarizes the grading and quantitative evaluation methods for TCM decoction pieces in recent years, proposing a comprehensive evaluation method based on the “Shape-Quality-Efficacy” theory. This method integrates multiple factors, including the external morphology, physicochemical properties, and pharmacological efficacy of TCM, providing a more comprehensive evaluation of the overall quality of decoction pieces. It offers a reference for establishing a quality evaluation system for TCM decoction pieces and provides a theoretical foundation for future research on the evaluation methods for TCM decoction pieces.

【基金】 国家中医药管理局科技司-浙江省中医药管理局共建科技计划项目(GZY-ZJ-KJ-24050);浙江省软科学研究计划项目(2024C25037,2024C35113,2024C35128);浙江省中医药科技计划项目(2023ZF048);浙江中医药大学科研项目资助(2023FSYYZZ17)
  • 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,2025年02期
  • 【分类号】R288
  • 【下载频次】118
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