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痰瘀清茶预防颅内外动脉支架置入术后再狭窄的临床研究

Clinical Study on the Prevention of Restenosis After Intracranial and Extracranial Artery Stenting with Tanyu Qingcha

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【作者】 林培贤张松涛黄海松陈炳煌林宝华

【Author】 LIN Peixian;ZHANG Songtao;HUANG Haisong;CHEN Binghuang;LIN Baohua;Department of Encephalopathy, Anxi County Hospital of Traditional Chinese Medicine;Department of Internal Medicine, Anxi County Chengxi Community Health Service Center;

【通讯作者】 林培贤;

【机构】 安溪县中医院脑病科安溪县城西社区服务中心内科

【摘要】 目的 探究痰瘀清茶预防颅内外动脉支架置入术后再狭窄的临床效果。方法 选取2023年3月至2024年10月在安溪县中医院拟行颅内外动脉支架置入术的患者60例,用随机数字表法将其分为两组,即对照组(30例,双联抗血小板聚集药物治疗)、治疗组(30例,双联抗血小板聚集药物+痰瘀清茶治疗),连续干预6个月。对比两组生活质量(WHOQOL-Bref)、实验室检查指标、不良反应发生情况、术后再狭窄发生率及并发症发生率。结果 治疗组的术后再狭窄发生率低于对照组(P<0.05);治疗后3个月、治疗后6个月,治疗组WHOQOL-Bref评分均高于对照组(P<0.05);治疗后3个月、治疗后6个月,治疗组的血常规指标、凝血功能指标、肝功能指标、肾功能指标与对照组相比,差异均无统计学意义(P > 0.05)。两组不良反应发生率和药物不良反应量表(TESS)评分以及并发症发生率比较,差异均无统计学意义(P > 0.05)。结论 痰瘀清茶能提高颅内外动脉支架置入术后再狭窄的预防效果,有效改善患者的生活质量,且应用较为安全。

【Abstract】 Objective To explore the clinical effect of Tanyu Qingcha in preventing restenosis after intracranial and extracranial artery stent implantation. Methods Sixty patients who were scheduled to undergo intracranial and extracranial arterial stent implantation at Anxi County Traditional Chinese Medicine Hospital from March 2023 to October 2024 were selected and randomly divided into two groups using a random number table: a control group(30 cases, treated with dual antiplatelet aggregation drugs) and a treatment group(30 cases, treated with dual antiplatelet aggregation drugs and Tanyu Qingcha), with continuous intervention for 6 months. Compare the quality of life(WHOQOL-Bruf), laboratory examination indicators, incidence of adverse reactions, incidence of postoperative restenosis, and incidence of complications between two groups. Results The incidence of postoperative restenosis in the treatment group was lower than that in the control group(P<0.05), After 3 months and 6 months of treatment, the WHOQOL Bruf scores in the treatment group were higher than those in the control group(P<0.05), After 3 months and 6 months of treatment, the blood routine indicators, coagulation function indicators, liver function indicators, and renal function indicators of the treatment group were all P>0.05 compared with the control group,There was no statistically significant difference. There was no statistically significant difference in the incidence of adverse reactions, Treatment Emergent Symptom Scale(TESS) scores, and incidence of complications between the two groups(P>0.05). Conclusions Tanyu Qingcha can improve the preventive effect of restenosis after intracranial and extracranial artery stent implantation, effectively improve the quality of life of patients, and is relatively safe to use.

【基金】 安溪县卫生健康局科技计划项目(2023AX120)
  • 【文献出处】 中国医药指南 ,Guide of China Medicine , 编辑部邮箱 ,2025年34期
  • 【分类号】R269
  • 【下载频次】3
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