【摘要】 1例患者确诊弥漫大B细胞淋巴瘤1个月、肢体麻木1周入院治疗。入院后给予维生素B₁片、甲钴胺片营养神经对症治疗后肢体麻木症状较前好转，后给予利妥昔单抗注射液、来那度胺胶囊和醋酸泼尼松片方案化疗后肢体麻木症状较前愈发明显，临床药师结合患者既往用药史并查阅资料分析，该患者的肢体麻木为来那度胺引起的周围神经病变。更多还原

【Abstract】 The patient was admitted to the hospital with a diagnosis of diffuse large B-cell lymphoma for one month, accompanied by limb numbness for one week. Upon admission, the patient was initially prescribed vitamin B₁ and mecobalamin for symptomatic relief, which led to an improvement in the symptoms of limb numbness. Subsequently, the patient was administered chemotherapy consisting of rituximab, lenalidomide, and prednisone. However, following the initiation of chemotherapy, the symptoms of limb numbness became more severe. After review of the patient’s medication history and analysis of relevant data, the clinical pharmacist suggested that the patient’s limb numbness was caused by lenalidomide-induced peripheral neuropathy.更多还原