【摘要】 目的 了解2018-2023年厦门市居民脑卒中及其不同分型的发病与死亡趋势，为政府制定脑卒中防控策略提供科学依据。方法 收集2018-2023年厦门市居民脑卒中的发病和死亡资料，计算粗发病率和粗死亡率，采用第六次全国人口普查数据进行标化，计算标化发病率和标化死亡率，采用χ~2检验进行组间比较，运用JoinPoint模型计算平均年度变化百分比(AAPC)。结果 2018年厦门市居民脑卒中粗发病率为506.25/10万(标化发病率568.49/10万),2023年的粗发病率为360.47/10万(标化发病率309.35/10万),2018-2023年脑卒中粗发病率(AAPC=-9.68%,P=0.044)和标化发病率(AAPC=-11.74%,P=0.026)均呈下降趋势；2018年厦门市居民脑卒中粗死亡率25.92/10万(标化死亡率22.59/10万),2023年的粗死亡率为34.03/10万(标化死亡率27.33/10万),粗死亡率(AAPC=3.23%,P=0.729)和标化死亡率(AAPC=0.46%,P=0.973)均没有明显变化趋势。其中，脑梗死标化发病率呈下降趋势(AAPC=-12.23%,P=0.025),标化死亡率没有明显变化(AAPC=-0.79%,P=0.945);脑出血标化发病率(AAPC=-9.69%,P=0.119)和标化死亡率(AAPC=-2.92%,P=0.701)都没有明显变化。男性脑卒中的粗发病率和标化发病率均高于女性(χ~2=4.988、4.090,P<0.05);脑卒中的粗发病率和粗死亡率都随着年龄的增大而增大(χ~2=148.288、40.440,P<0.01)。结论 厦门市脑卒中(特别是脑梗死)的发病率呈现了逐年下降的趋势，男性发病率高于女性，且随年龄增长发病率和死亡率增加。更多还原

【Abstract】 Objective To understand and analyze the incidence and mortality trends of stroke and its different subtypes among residents in Xiamen city from 2018 to 2023,so as to provide scientific basis for the government to formulate stroke prevention and control strategies. Methods Data on stroke incidence and mortality among Xiamen residents from 2018 to 2023 were collected.Crude incidence and mortality rates were calculated.Rates were standardized using data from the Sixth National Population Census to obtain age-standardized incidence and mortality rates.Intergroup comparisons were performed using the χ~2 test.The Average Annual Percent Change(AAPC) was calculated using the JoinPoint model. Results The crude incidence rate of stroke among Xiamen residents in 2018 was 506.25/10~5(standardized incidence rate 568.49/10~5),and the crude incidence rate in 2023 was 360.47/10~5(standardized incidence rate 309.35/10~5).From 2018 to 2023,both the crude incidence rate and standardized incidence rate of stroke showed a downward trend(AAPC=-9.68%,P=0.044;AAPC=-11.74%,P=0.026);The crude mortality rate of stroke among residents in Xiamen in 2018 was 25.92/10~5(standardized mortality rate 22.59/10~5),and the crude mortality rate in 2023 was 34.03/10~5(standardized mortality rate 27.33/10~5).There was no significant change in both crude and standardized mortality rates(AAPC=-3.23%,P=0.729;AAPC=0.46%,P=0.973).Among them, ischemic stroke has a downward trend in the standardized incidence rate(AAPC=-12.23%,P=0.025),and the standardized mortality rate did not change significantly(AAPC=-0.79%,P=0.945);There was no significant change in the standardized incidence rate and mortality of hemorrhagic stroke(AAPC=-9.69%,-2.92%,P=0.119,0.701).The crude incidence and standardized incidence rate of stroke in men were higher than those in women(χ~2=4.988,4.090,P<0.05),while there was no significant difference in crude mortality and standardized mortality between men and women(χ~2=0.007,1.225,P= 0.935,0.268);The crude incidence rate and crude mortality rate of stroke increased with age(χ~2=148.288,40.440,P<0.01). Conclusion The incidence rate of stroke(particularly cerebral infarction) in Xiamen city showed a year-by-year declining trend.The incidence rate was higher in males than in females, and both incidence and mortality rates increased with age.更多还原