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绵阳市高龄老人和长寿老人HIV抗体确证试验结果分析

Analysis of HIV antibody confirmatory test results in the oldest old and the longevous in Mianyang City

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【作者】 李川; 杨红; 罗成瑞; 林宇飞; 许倩倩; 王东霞; 罗赟;

【Author】 LI Chuan;YANG Hong;LUO Chengrui;LIN Yufei;XU Qianqian;WANG Dongxia;LUO Yun;Department of Service Quality Management,Mianyang City Center for Disease Control and Prevention;

【通讯作者】 罗赟;

【机构】 绵阳市疾病预防控制中心业务质量管理科; 绵阳市疾病预防控制中心微生物与临床检验所;

【摘要】 目的 回顾统计分析绵阳市高龄老人和长寿老人人类免疫缺陷病毒(HIV)抗体确证试验检测结果,为艾滋病防控策略提供参考依据。方法 收集绵阳市筛查实验室上送的2017—2022年高龄老人和长寿老人HIV抗体初筛阳性样本,使用免疫印迹法进行HIV抗体确证试验,采用χ~2检验进行组间比较。结果 662例样本中,HIV抗体确证试验结果为阳性的453例,阳性率为68.43%,检测HIV抗体确证试验结果为不确定的100例,占15.11%,HIV抗体确证试验结果为阴性的109例,占16.47%;HIV抗体确证试验结果为阳性的,男女性别比约为6∶1,不同性别高龄老人和长寿老人HIV抗体确证试验结果,差异有统计学意义(χ~2=53.256,P<0.001);全市各地均有HIV抗体初筛阳性样本送检,不同区域HIV抗体确证试验结果差异有统计学意义(χ~2=71.774,P<0.001);来源为自愿咨询检测、感染者家属样本的HIV抗体确证试验阳性率均为100.00%,不同样本来源样本的HIV抗体确证试验结果,差异有统计学意义(χ~2=28.041,P=0.002);HIV抗体初筛阳性样本,疾病预防控制机构送检样本的HIV抗体确证试验阳性率最高,为75.10%,其次为三级甲等医院送检样本的HIV抗体确证试验阳性率为68.29%,不同类型的送检单位HIV抗体确证试验结果差异有统计学意义(χ~2=30.448,P=0.001)。结论 要加强对高龄老人和长寿老人的健康教育和艾滋病筛查工作,特别是老年男性;要关注高龄老人和长寿老人的身心健康,重视预防和干预工作。

【Abstract】 Objective To review and statistically analyze the results of Human immunodeficiency virus(HIV) antibody confirmatory test in the oldest old and the longevous in Mianyang City, and to provide a reference basis for AIDS prevention and control strategies.Methods Positive samples for primary screening HIV antibodies were collected from 2017 to 2022 from the oldest old and the longevous uploaded by screening laboratories in Mianyang City.The HIV antibody confirmatory test was performed using Western blotting, and the Chi-square test was used for between-group comparison.Results Of the 662 samples, 453 cases were positive in the HIV antibody confirmatory test, accounting for a positive rate of 68.43%.The result of the HIV antibody confirmatory test was uncertainty in 100 cases, accounting for 15.11%,and the results of the HIV antibody confirmatory test was negative in 109 cases, accounting for 16.47%.The gender ratio of male to female with positive HIV antibody confirmatory test results was about 6∶1.There was a statistically significant difference between the results of the HIV antibody confirmatory test in the oldest old and the longevous of different genders(χ~2=53.256,P<0.001).Primary positive samples of HIV antibodies were sent from all regions of the city, and the difference in the results of HIV antibody confirmatory test in different regions was statistically significant(χ~2=71.774,P<0.001).The positive rate of HIV antibody confirmatory test for samples sourced from voluntary counseling and testing and family members of infected individuals were all 100.00%. There was a statistically significant difference between the results of the HIV antibody confirmatory tests for samples from different sample sources(χ~2=28.041,P=0.002).For primary positive samples of HIV antibody screening, the positive rate of HIV antibody confirmatory test was the highest for samples sent by the disease prevention and control institutions, accounting for 75.10%. Followed by the positive rate of the HIV antibody confirmatory test for samples sent by third grade first class hospital was 68.29%.There was a statistically significant difference in the results of the HIV antibody confirmatory test between the different types of sending units(χ~2=30.448, P=0.001).Conclusion Health education and AIDS screening should be strengthened for the oldest old and the longevous, especially for aging male.Attention should be paid to the physical and mental health of the oldest old and the longevous, and emphasis should be placed on prevention and intervention work.

【基金】 中华预防医学会2025—2026年社会组织参与艾滋病防治基金干预关怀项目(2025—2026510703PYDFSW503275C);2025年度市级社会科学研究规划项目(MY2025YB019)
  • 【文献出处】 医学动物防制 ,Journal of Medical Pest Control , 编辑部邮箱 ,2025年10期
  • 【分类号】R512.91
  • 【下载频次】52
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