【摘要】 目的 了解安徽省2个山丘型血吸虫病流行区野鼠的血吸虫感染状况，为血吸虫病防治策略的制定提供依据。方法 选择安徽省池州市2个山丘型血吸虫病流行区(贵池区和石台县),每个县(区)分别选择1个有感染性钉螺分布的村为观察村，未发现感染性钉螺的村为对照村。采取夹夜法捕获野鼠，计算鼠密度。采用肝脏组织压片镜检、肠系膜组织镜检和改良加藤厚涂片法(Kato-katz法)检测野鼠血吸虫的感染情况，并利用χ~2检验比较不同鼠种日本血吸虫的感染率差异。结果 贵池区观察村(栗坑村),共捕获黑线姬鼠、黄毛鼠、黄胸鼠、褐家鼠和社鼠5种野鼠，鼠密度为4.44%,日本血吸虫感染率为39.56%,不同种类野鼠日本血吸虫的感染率差异有统计学意义(χ~2=7.584,P=0.023);对照村(龙池村)的鼠密度为2.24%,未发现野鼠日本血吸虫感染。石台县观察村(东庄村),共捕获黑线姬鼠、黄毛鼠、褐家鼠和社鼠4种野鼠，鼠密度为11.73%,日本血吸虫感染率为46.90%,不同种类野鼠日本血吸虫的感染率差异有统计学意义(χ~2=10.637,P=0.014);对照村(七都村)鼠密度为8.78%,未发现野鼠感染日本血吸虫。结论 安徽部分山丘地区野鼠种类多、密度高、血吸虫感染率高，其可能是血吸虫病传播的潜在传染源，应加强监测。更多还原

【Abstract】 Objective To understand the status of schistosomiasis infection in wild mice in two hilly schistosomiasis endemic regions of Anhui Province, and to provide a basis for the formulation of strategies for schistosomiasis prevention and control.Methods Two hilly schistosomiasis endemic regions(Guichi District and Shitai County) in Chizhou City of Anhui Province were selected.In each county(district),one village with the distribution of infected snails was selected as the observation village, and one village without infected snail as the control village.The wild mice were captured using the night trapping method and the densities of mice were calculated.Liver tissues slide microscopy, mesenteric tissue microscopy and Kato-katz method were used to detect Schistosoma infections in wild mice.The differences in infection rates of Schistosoma japonicum among different mouse species were compared using the Chi-square test.Results Five species of wild mice were captured in the observation village of Guichi District(Likang Village),namely, Apodemus agrarius,Rattus losea,Rattus flavipectus,Rattus norvegicus,and Niviventer confucianus.The density of mice was 4.44%.The infection rate of Schistosoma japonicum was 39.56%.There was a statistically significant difference(χ~2=7.584,P=0.023) in the infection rate of Schistosoma japonicum among different species of wild mice.In the control village(Longchi Village),the density of mice was 2.24%,and no wild mice were found to be infected with Schistosoma japonicum.In the observation village(Dongzhuang Village) of Shitai County, four species of wild mice(Apodemus agrarius,Rattus losea,Rattus norvegicus,and Niviventer confucianus) were captured.The density of mice was 11.73% and the infection rate of Schistosoma japonicum was 46.90%.There was a statistically significant difference(χ~2=10.637,P=0.014) in the infection rate of Schistosoma japonicum among different species of wild mice.In the control village(Qidu Village),the density of mice was 8.78%,and no wild mice were found to infected with Schistosoma japonicum.Conclusion In some hilly areas of Anhui Province, there are many species of wild mice with high densities and high infection rate of Schistosoma.Wild mice may be a potential infection source of transmission of schistosomiasis.Surveillance should be strengthened.更多还原