【摘要】 目的 探讨正性暗示联合人性化干预对胆囊结石合并急性胆囊炎行腹腔镜胆囊切除术患者免疫功能的影响。方法 选取2020年7月至2023年7月本院78例行腹腔镜胆囊切除术的胆囊结石合并急性胆囊炎患者进行回顾性分析，按照护理干预方法的不同将其分为A组（39例，常规护理干预）和B组（39例，正性暗示联合人性化干预）。比较两组的干预效果。结果 B组的手术时间、术后排气时间及住院时间短于A组，术中出血量少于A组（P<0.05）。术后3 d，两组的CD3~+、CD4~+及CD4~+/CD8~+均低于术前，CD8~+高于术前（P<0.05）；术后3 d,B组的CD3~+、CD4~+及CD4~+/CD8~+稍高于A组，CD8~+稍低于A组，差异无统计学意义（P>0.05）。术后3 d，两组的焦虑自评量表（SAS）、抑郁自评量表（SDS）及疼痛数字评分法（NRS）评分均低于术前，且B组低于A组（P<0.05）。B组的并发症总发生率稍低于A组，但差异无统计学意义（P>0.05）。B组的护理满意度为97.44%，高于A组的79.49%，差异具有统计学意义（P<0.05）。结论 正性暗示联合人性化干预应用于胆囊结石合并急性胆囊炎行腹腔镜胆囊切除术患者中不会增加对免疫功能的损伤，可缓解焦虑、抑郁情绪，减轻疼痛程度，且安全性良好，护理满意度更高。更多还原

【Abstract】 Objective To investigate the effect of positive suggestion combined with humanized intervention on immune function in patients with cholecystolithiasis complicated with acute cholecystitis undergoing laparoscopic cholecystectomy. Methods A retrospective analysis was performed on 78 patients with cholecystolithiasis complicated with acute cholecystitis who underwent laparoscopic cholecystectomy in our hospital from July 2020 to July 2023. According to different nursing intervention methods, the patients were divided into group A(39 cases, routine nursing intervention) and group B(39 cases, positive suggestion combined with humanized intervention). The intervention effects of the two groups were compared. Results The operation time, postoperative exhaust time and hospitalization time of the group B were shorter than those of the group A, and the intraoperative blood loss was less than that of the group A(P<0.05). At 3 d after operation,the CD3~+ , CD4~+ and CD4~+ /CD8~+ in the two groups were lower than those before operation, and the CD8~+ was higher than that before operation(P<0.05); at 3 d after operation, the CD3~+ , CD4~+ and CD4~+ /CD8~+ in the group B were slightly higher than those in the group A, and the CD8~+ was slightly lower than that in the group A, and the differences were not statistically significant( P > 0. 05). At 3 d after operation, the scores of Self-Rating Anxiety Scale(SAS), Self-Rating Depression Scale(SDS) and Numerical Rating Scale(NRS) in the two groups were lower than those before operation, and those in the group B were lower than the group A(P<0.05). The total incidence of complications in the group B was slightly lower than that in the group A, but the difference was not statistically significant(P>0.05). The nursing satisfaction of the group B was 97.44%,which was higher than 79.49% of the group A, and the difference was statistically significant(P<0.05).Conclusion Positive suggestion combined with humanized intervention in patients with cholecystolithiasis complicated with acute cholecystitis undergoing laparoscopic cholecystectomy will not increase the damage of immune function, it can relieve anxiety and depression, reduce the degree of pain, and has good safety and higher nursing satisfaction.更多还原