【摘要】 目的 了解四川省医学放射工作人员的甲状腺功能状况，分析放射因素对甲状腺功能的影响，为调整防控措施提供参考。方法 收集了2023—2024年四川省医学放射工作人员的职业健康检查结果，分析其甲状腺功能水平及异常情况。使用SPSS 20.0软件进行数据分析，计量资料采用秩和检验，计数资料采用χ²检验，多因素分析采用二元Logistic回归模型，检验水准α=0.05。结果 共调查3 288名医学放射工作人员，女性FT3、FT4中位值(4.38 pmol·L^-1、15.21 pmol·L^-1)低于男性(5.05 pmol·L^-1、16.21 pmol·L^-1),TSH中位值(2.41 mIU·L^-1)高于男性(2.14 mIU·L^-1)（Z=-23.677、-11.894,-6.724,P<0.001）;30～<40岁、≥40岁人员的FT4中位值(15.80 pmol·L^-1、15.60 pmol·L^-1)，均低于<30岁人员(16.09pmol·L^-1)（P<0.05）；不同职业类别人员FT3、FT4水平差异有统计学意义（H=27.416,26.204,P<0.001）；工龄4～<8年、≥8年人员的FT4中位值(15.64 pmol·L^-1、15.65 pmol·L^-1)，均低于工龄<4年人员(16.03 pmol·L^-1)（P<0.05）。二元Logistic回归分析显示，女性（OR=1.748,95%CI:1.373～2.224,P<0.001）、年龄≥40岁（OR=1.915,95%CI:1.282～2.860,P=0.002）及工龄4～<8年（OR=1.482,95%CI:1.064～2.063,P=0.020）放射工作人员甲状腺功能异常风险更高。结论 长期辐射暴露对医学放射工作人员的甲状腺功能水平存在一定影响，其中女性、年龄≥40岁及工龄为4～7年的工作人员值得关注。建议定期监测其甲状腺功能指标，以切实保障放射工作人员的职业健康。更多还原

【Abstract】 Objective To understand the thyroid function status of medical radiation workers in Sichuan Province, analyze the impact of radiation exposure on thyroid function, and to provide a references for adjusting prevention and control measures. Methods Occupational health examination results of medical radiation workers in Sichuan Province from 2023 to 2024 were collected, and their thyroid function levels and abnormalities were analyzed. SPSS 20.0 software was used for data analysis. The rank sum test was used for measurement data,the χ² test was used for enumeration data, and the Binary Logistic Regression Model was used for multivariate analysis. The test level was α = 0.05. Results A total of 3288 medical radiology workers were investigate. The median values of FT3 and FT4 in females(4.38 pmol · L^-1,15.21 pmol·L^-1) were lower than those in males(5.05 pmol·L^-1,16.21 pmol·L^-1),while the median TSH value(2.41 mIU·L^-1) was higher than that in males(2.14 m IU · L^-1)（Z=-23.677,-11.894,-6.724,P<0.001）;The median FT4values(15.80 pmol·L^-1,15.60 pmol·L^-1) of individuals aged 30-<40 and ≥40 were lower than those of individuals aged<30(16.09 pmol · L^-1)（P<0.05）; There was a statistically significant difference in the levels of FT3 and FT4 among personnel from different occupational categories（H=27.416, 26.204, P<0.001）; The median FT4 values(15.64 pmol · L^-1, 15.65 pmol · L^-1) of personnel with 4-<8 years of service and ≥8 years of service were lower than those with less than<4 years of service(16.03 pmol · L^-1)（P<0.05）. Binary Logistic Regression analysis showed that women（OR=1.748, 95% CI: 1.373-2.224, P<0.001）, age≥40 years（OR=1.915, 95% CI:1.282-2.860, P=0.002）, and work experience of 4～<8 years（OR=1.482, 95% CI: 1.064-2.063,P=0.020） had a higher risk of thyroid dysfunction in radiation workers. Conclusion Long-term radiation exposure has a certain impact on the thyroid function levels of medical radiology workers,with attention needed for female workers, aged≥40, and those with 4-<8 years of work experience. It is recommended to regularly monitor their thyroid function indicators to effectively protect the occupational health of radiology workers.更多还原