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“流域血管栓塞”概念的提出及其在血管介入治疗中的临床应用及意义

The Proposal of the Concept of “Watershed Vascular Embolization” and Its Clinical Application and Significance in Vascular Interventional Therapy

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【作者】 崔伟李静钟文昭周海榆陈晓明张绪超许荣德

【Author】 CUI Wei;LI Jing;ZHONG Wen-zhao;ZHOU Hai-yu;CHEN Xiao-ming;ZHANG Xu-chao;XU Rong-de;Department of Interventional Radiology,Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences),Southern Medical University;Department of Pulmonary and Critical Care Medicine,Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences),Southern Medical University;Guangdong Lung Cancer Institute,Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences),Southern Medical University;Department of Thoracic Surgery,Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences),Southern Medical University;

【通讯作者】 许荣德;

【机构】 南方医科大学附属广东省人民医院(广东省医学科学院)微创介入科南方医科大学附属广东省人民医院(广东省医学科学院)呼吸与危重症医学科南方医科大学附属广东省人民医院(广东省医学科学院)广东省肺癌研究所南方医科大学附属广东省人民医院(广东省医学科学院)胸外科

【摘要】 经动脉栓塞与灌注术是治疗出血、脉管畸形及良恶性肿瘤等疾病的基石性介入手段。然而,现行手术命名体系,如“肝动脉灌注化疗术”和“支气管动脉栓塞术(bronchial artery embolization,BAE)”,存在一个根本性局限:其以单一靶动脉命名,在概念上固化了术者对治疗目标的认知,却忽略了病灶的实际血供是一个由多源动脉及其侧支构成的动态三维网络。这一认知偏差是导致术后复发率高、疗效不理想及异位栓塞等并发症的共同根源之一。为解决此系统性问题,本文基于血管解剖学、血流动力学原理及临床实践,提出一个普适性的新概念——“流域血管栓塞”。该理论将滋养病灶的完整血供单元定义为“流域血管”,强调治疗目标应从栓塞单一血管转变为管理整个动态血供网络。本文以传统BAE为例,系统阐述该概念的内涵与临床意义,旨在重塑血管介入治疗思维,为提升血管介入治疗的彻底性、安全性及远期疗效提供全新的理论范式与实践指导。

【Abstract】 Transarterial embolization and infusion therapy are foundational interventions for conditions including hemorrhage, vascular malformations, and benign/malignant tumors. However, the prevailing nomenclature for these procedures(e.g., “hepatic arterial infusion chemotherapy”, “bronchial artery embolization, BAE”) suffers from a fundamental limitation: naming conventions based on a single target artery conceptually constrain the therapeutic objective, overlooking the pathological reality that lesion perfusion is sustained by a dynamic, three-dimensional network of multiple arterial sources and collateral channels. This cognitive bias is a common underlying cause of high postoperative recurrence rates, suboptimal efficacy, and complications such as non-target embolization. To address this systemic issue, this paper introduces a universal new theory—“watershed vascular embolization”—based on vascular anatomy, hemodynamic principles, and clinical practice. This theory defines the complete functional blood supply unit of a lesion as a “watershed vascular”, advocating for a shift in therapeutic focus from occluding individual vessels to managing the entire dynamic perfusion network. Using conventional BAE as a paradigm, this article elaborates the conceptual framework and clinical significance of watershed vascular embolization, aiming to reshape interventional thinking and provide a novel theoretical paradigm and practical guidance for enhancing the thoroughness, safety, and longterm outcomes of vascular intervention.

【基金】 国家重点研发计划子课题(2023YFC2507104);国家科技重大专项子课题(2024ZD0526705)
  • 【文献出处】 循证医学 ,The Journal of Evidence-Based Medicine , 编辑部邮箱 ,2025年06期
  • 【分类号】R815
  • 【下载频次】7
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