【摘要】 目的:探究在老年糖尿病视网膜病变(DR)治疗中联用康柏西普注射液与依帕司他片的效果。方法:选取2023年8月至2024年7月贵港市人民医院收治的80例老年DR患者,随机分为两组,每组各40例。两组均采用康柏西普注射液进行治疗,观察组加用依帕司他片进行治疗。结果:观察组治疗的总有效率高于对照组(P <0.05)。治疗后,观察组最佳矫正视力(BCVA)、超氧化物歧化酶(SOD)及总抗氧化能力(TAC)水平高于对照组(P <0.05),黄斑中心视网膜厚度(CMT)小于对照组(P <0.05),丙二醛(MDA)、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)水平低于对照组(P <0.05)。结论:康柏西普注射液联合依帕司他片在老年DR的治疗中效果显著,值得临床推广。更多还原

【Abstract】 Objective: To evaluate the efficacy of Conbercept combined with Epalrestat in elderly diabetic retinopathy(DR). Methods: 80 elderly DR patients(August 2023–July 2024) were randomized into two groups(n=40 each). Both received Conbercept; the observation group additionally received Epalrestat. Results: The observation group had higher total efficacy, BCVA, SOD, TAC, and lower CMT, MDA, TNF-α, and IL-6 levels(all P < 0.05). Conclusion: The combination therapy improves visual and biochemical outcomes in elderly DR.更多还原