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麻醉治疗失眠:创新、机遇和挑战

Anesthesiology in the treatment of insomnia: innovative, opportunities, and challenges

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【作者】 郑婷薇胡静萍邢纪斌李响程楠许剑张岳农周少丽

【Author】 ZHENG Tingwei;HU Jingping;XING Jibin;LI Xiang;CHENG Nan;XU Jian;ZHANG Yuenong;ZHOU Shaoli;Department of Anaesthesia and Nerve Block Pain Treatment for Sleep Disorders, Sleep Medicine Center, the Third Affiliated Hospital of Sun Yat-sen University;Pain Sleep Center, the Third Affiliated Hospital of Sun Yat-sen University,Yuedong Hospital;

【通讯作者】 张岳农;周少丽;

【机构】 中山大学附属第三医院睡眠医学中心睡眠障碍麻醉与神经阻滞疼痛治疗分部中山大学附属第三医院粤东医院疼痛睡眠中心

【摘要】 失眠作为一种普遍的睡眠障碍,不仅影响患者的夜间休息,也给其日常生活带来深远的负面影响。认知行为疗法和药物治疗是常规治疗手段,而近年来麻醉学在失眠治疗中的应用潜力也日益受到关注。麻醉科医师凭借其对镇静药物的深刻理解,能够为慢性和顽固性失眠患者量身定制治疗方案。已有研究表明,麻醉药物(如丙泊酚、右美托咪定)以及星状神经节阻滞能够有效改善睡眠结构,缓解睡眠剥夺的负面效应。然而,麻醉治疗在失眠管理中的应用仍面临技术要求高、治疗标准不统一等挑战。随着麻醉学治疗体系的不断发展,整合多学科治疗方法并制定规范化治疗标准,将有助于这一领域的拓展和普及。

【Abstract】 Insomnia is a common sleep disorder that significantly impacts daily functioning and overall health. Traditional treatments, including Cognitive Behavioral Therapy for Insomnia(CBT-I) and pharmacotherapy, are widely used; however, anesthesiology, as an emerging treatment modality, has shown promising potential due to its precise drug management and unique technical advantages. Anesthesiologists can offer personalized treatments using sedative-hypnotic drugs and nerve block techniques, particularly for chronic and refractory insomnia. Innovations such as propofol, dexmedetomidine, and stellate ganglion block have been shown to regulate sleep architecture, improve sleep quality, and quickly reverse sleep deprivation, breaking the vicious cycle of insomnia. Despite these promising results, challenges remain, including technical complexity, the need for standardized protocols, and long-term efficacy evaluation. In the future, with the standardization of anesthetic techniques, multidisciplinary collaboration, and the integration of emerging technologies, anesthesiology is expected to play a greater role in insomnia treatment.

【基金】 广东省基础与应用基础研究基金企业联合基金(2021A1515220061);广东省医学会研究基金(2022375);广东省医院药学研究基金(2020XC06)
  • 【文献出处】 新医学 ,Journal of New Medicine , 编辑部邮箱 ,2025年02期
  • 【分类号】R740
  • 【下载频次】60
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