【摘要】 癌症本身和抗肿瘤治疗都会影响血脂的代谢与水平，导致心血管疾病风险增加。低密度脂蛋白胆固醇作为心血管疾病的独立危险因素，其与癌症患者预后的关联日益受到关注。因此有必要对癌症患者中脂质代谢的特征、作用与管理现状开展系统探讨。现从癌症患者的发病率、死亡率等流行病学数据，癌症患者脂质代谢与肿瘤发展的相互作用机制，血脂水平影响预后的多角度研究和癌症患者的血脂管理四个方面开展综述，以阐明血脂水平与癌症患者病程、预后及综合治疗的关系，并为未来更广泛人群的研究方向提供潜在线索。更多还原

【Abstract】 Cancer itself and antineoplastic therapies will affect the metabolism and level of plasma lipid, leading to an increase in the risk of cardiovascular disease.Low-density lipoprotein cholesterol, a well-established independent predictor of cardiovascular disease, has garnered increasing attention regarding its association with cancer patients’ prognosis.Therefore, it is necessary to conduct a systematic discussion on the characteristics, functions and management status of lipid metabolism in cancer patients.This article is divided into the following four aspects to explain: epidemiological data such as incidence and mortality of cancer patients, the interaction mechanism between lipid metabolism and tumor development in cancer patients, multi-angle research on the impact of plasma lipid levels on prognosis in cancer patients and the clinical management of plasma lipid.This analysis aims to elucidate the relationship between plasma lipid levels and disease progression, clinical outcomes, and comprehensive treatment efficacy in cancer patients.Furthermore, it seeks to identify potential research directions in broader populations for future investigations.更多还原