【摘要】 旨在探索犬离体肌肉组织微波消融(MWA)形成的消融区域大小与消融功率、消融持续时间之间的关系，通过回归分析建立消融区域的预测模型，为MWA技术的兽医临床应用提供理论支持。以不同消融功率和消融持续时间的组合对48块犬离体肌肉进行MWA，通过超声波(US)、电子计算机断层扫描(CT)和直接测量方法评估消融区域的纵径、横径及前后径，回归分析后，探索消融功率、消融持续时间与消融区域大小之间的关系，构建多元线性回归模型。结果:消融功率和消融持续时间与消融区域大小呈显著正相关。回归分析构建了6个不同条件下的预测方程式，所有方程的决定系数(R~2)均接近或大于0.5，具有较好的预测能力。回归模型显示，功率和时间的增加均会导致消融区域的增大。直接测量结果与超声测量结果差异不显著(P>0.05)，与CT测量值存在显著差异(P<0.05)。本研究成功建立了肌肉组织基于消融功率和时间的消融区域预测模型，能够为MWA技术的临床应用提供理论依据。更多还原

【Abstract】 This study explored the relationship between the size of the microwave ablation( MWA) zone formed in canine ex vivo muscle tissue and the ablation power and duration. A predictive model for the ablation zone was also established through regression analysis to provide theoretical support for the clinical application of the MWA technology in veterinary medicine. In this study,MWA was performed on canine ex vivo muscle tissue using different combinations of ablation power and duration. The longitudinal,transverse,and anteroposterior diameters of the ablation zone were evaluated using ultrasound,CT,and direct measurement methods. Regression analysis was conducted to explore the relationship between ablation power,duration,and the size of the ablation zone; and a multiple linear regression model was constructed. The results showed that ablation power and duration were significantly positively correlated with the size of the ablation zone. The regression analysis generated six predictive equations under different conditions,with the coefficient of determination( R~2) for all equations being close to or greater than 0. 5,indicating good predictive capability. The regression model demonstrated that increases in both the power and duration led to an enlargement of the ablation zone. Furthermore,the ultrasound measurements were relatively consistent with the direct measurements,while the CT measurements showed some discrepancies. To conclude,this study successfully established a predictive model for the ablation zone based on ablation power and duration,which provided a theoretical foundation for clinical application of the MWA technology.更多还原