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心房功能性二尖瓣反流的研究进展

Research Progress of atrial functional mitral regurgitation

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【作者】 赖红梅; 刘永; 陶静; 杨毅宁;

【Author】 LAI Hongmei;LIU Yong;TAO Jing;YANG Yining;Cardiovascular and Panvascular Medicine Diagnosis and Treatment Center, People’s Hospital of Xinjiang Uygur Autonomous Region;

【通讯作者】 杨毅宁;

【机构】 新疆维吾尔自治区人民医院心脏及泛血管医学诊疗中心,新疆心脏血管稳态与再生医学研究重点实验室;

【摘要】 本文深入探讨了心房功能性二尖瓣反流(atrial functional mitral regurgitation,AF-MR)的研究进展与展望,重点分析了其病理机制、诊断方法及治疗策略。在诊断方面,评估了超声心动图、磁共振成像(MRI)等影像学技术在AF-MR检测与定量分析中的优势与局限。此外,本文评估了包括药物治疗、经导管修复和外科手术在内的多种治疗方法的疗效与应用前景。本文还讨论了AFMR治疗中面临的挑战,如合适的患者选择标准和长期效果的评估,并提出了未来的研究方向,包括新型生物标志物的开发与个性化医疗的应用。

【Abstract】 This article provides an in-depth exploration of the research progress and future directions in atrial functional mitral regurgitation(AF-MR), with a focus on its pathological mechanisms, diagnostic approaches, and treatment strategies. In terms of diagnosis, it evaluates the strengths and limitations of imaging techniques such as echocardiography and magnetic resonance imaging(MRI) in the detection and quantitative assessment of AF-MR. Furthermore, the efficacy and application prospects of various treatment modalities, including pharmacological therapy, transcatheter repair, and surgical intervention, are examined. The article also discusses challenges in AF-MR management, such as appropriate patient selection criteria and the evaluation of long-term outcomes, and proposes future research directions, including the development of novel biomarkers and the implementation of personalized medicine.

【基金】 新疆维吾尔自治区天山英才培养计划项目(2022TSYCLJ0028)
  • 【文献出处】 新疆医学 ,Xinjiang Medical Journal , 编辑部邮箱 ,2025年09期
  • 【分类号】R654.2
  • 【下载频次】8
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