【摘要】 目的 研究老年前列腺癌患者营养状况并探讨相关影响因素。方法 将2020年1月1日-2022年12月31日本院收治的老年前列腺癌患者（n=92）作为研究对象，统计入选患者营养不良概率，并调取入选患者一般资料，对比营养不良与营养良好者的一般资料，将一般资料中有差异项带入Logistic回归方程，分析老年前列腺癌患者营养不良形成的原因，并给予针对性预防措施。结果 入选患者中，营养不良者占比36.13%。发生及未发生营养不良者在吞咽能力、手术、病理分期、放疗、化疗等方面均有差异，P<0.05，将上述因素带入Logistic回归方程计算发现，上述因素均是引起老年前列腺癌患者营养不良的影响因素。ROC曲线分析结果显示，吞咽能力1-3级、手术、病理分期高分化、放疗、化疗预测老年前列腺癌患者营养不良的AUC分别为0.752、0.763、0.767、0.737、0.644；灵敏度分别为73.3%、71.1%、73.3%、73.3%、64.4%，特异度分别为86.3%、82.4%、82.4%、80.4%、82.4%。结论 老年前列腺癌患者发生营养不良的风险较高，且吞咽能力1-3级、手术、病理分期高分化、放疗、化疗均为影响患者营养状况的危险因素，应加以重视并采取相应措施加以预防或改变患者营养不良的现状。更多还原

【Abstract】 Objective To study the nutritional status of elderly prostate cancer patients and explore the related influencing factors.Methods The elderly prostate cancer patients(n=92) admitted to our hospital from 2020.1.1 to 2022.12.31 were taken as the research subjects, the probability of malnutrition of the enrolled patients was counted, and the general information of the enrolled patients was retrieved, the general information of the malnourished and the well-nourished was compared, and the difference items in the general information were brought into the Logistic Regression Equation, so as to analyze the reasons for the formation of malnutrition in elderly prostate cancer patients and to give targeted preventive measures. We analyzed the causes of malnutrition in elderly patients with prostate cancer and provided targeted preventive measures.Results Among the enrolled patients, 36.13% were malnourished. There were differences between those who occurred and those who did not occur malnutrition in terms of swallowing ability, surgery, pathological staging, radiotherapy, chemotherapy, etc., with P<0.05. Calculating the above factors by bringing them into the Logistic Regression Equation, it was found that all of the above factors were the influencing factors causing malnutrition in elderly prostate cancer patients.The results of ROC curve analysis showed that the AUCs of swallowing ability grade 1-3, surgery, highly differentiated pathological stage, radiotherapy, and chemotherapy for predicting malnutrition in elderly prostate cancer patients were 0.752, 0.763, 0.767, 0.737,and 0.644, respectively; the sensitivities were 73.3%, 71.1%, 73.3%, 73.3%, and 64.4%, and the specificities were 86.3%, 82.4%,82.4%, 80.4%, 82.4%.Conclusion Elderly prostate cancer patients have a higher risk of malnutrition, and swallowing ability grade 1-3, surgery, high differentiation of pathological stage, radiotherapy, chemotherapy are all risk factors affecting the nutritional status of the patients, which should be emphasized and corresponding measures should be taken to prevent or change the current situation of malnutrition in the patients.更多还原