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GLP-1RA治疗2型糖尿病合并冠心病的最新研究进展
The Latest Research Progress of GLP-1RA in the Treatment of Type 2 Diabetes Mellitus Complicated with Coronary Heart Disease
【摘要】 随着2型糖尿病(T2DM)的不断进展,T2DM合并冠心病的发病率不断上升,对于此类患者仅单纯应用降糖治疗已无法满足其需求。T2DM合并冠心病的治疗一直以来都受到了广泛的关注,胰高血糖素样肽-1受体激动剂(GLP-1RA)是近些年来降糖治疗的热点研究课题,而在此基础上更具有明显的心血管保护作用,故而对于T2DM合并冠心病的治疗有一定的前景。本文分析了T2DM和冠心病的关系,并就GLP-1RA治疗T2DM合并冠心病的作用及该药应用的最新研究进展进行综述,旨在为临床医务人员治疗T2DM合并冠心病提供有效的依据。
【Abstract】 With the continuous progress of type 2 diabetes mellitus(T2DM), the incidence of T2DM complicated with coronary heart disease is increasing. For such patients, only hypoglycemic therapy cannot meet their needs. The treatment of T2DM with coronary heart disease has always been widely concerned. Glucagon-like peptide-1 receptor agonist(GLP-1RA) is a hot research topic in hypoglycemic therapy in recent years. As it has obvious cardiovascular protection, there is a certain prospect for the treatment of T2DM with coronary heart disease. This article analyzes the relationship between T2DM and coronary heart disease, and reviews the latest research progress of GLP-1 RA in the treatment of T2DM with coronary heart disease and the application of this drug, aiming to provide an effective basis for clinical medical staff in the treatment of T2 DM with coronary heart disease.
【Key words】 Glucagon-like peptide-1 receptor agonist; Cardiovascular protection; Type 2 diabetes; Coronary heart disease;
- 【文献出处】 现代诊断与治疗 ,Modern Diagnosis and Treatment , 编辑部邮箱 ,2025年05期
- 【分类号】R541.4;R587.1
- 【下载频次】16