【摘要】 目的 系统评价中国高校大学生HPV疫苗接种意愿及其影响因素。方法 计算机检索PubMed、Web of Science、Embase、The Cochrane Library、PsycINFO、CINAHL、SinoMed、中国知网、维普和万方数据库建库至2025年3月12日的相关研究，采用Stata 17.0和RevMan 5.4对大学生HPV疫苗接种意愿及其影响因素进行Meta分析。结果 纳入35项研究，涉及62 958例样本量。Meta分析数据表明，中国高校大学生HPV疫苗接种意愿为67.0%。女性(OR=3.47,95%CI:2.49～4.85)、有性行为史(OR=1.91,95%CI:1.09～3.35)、接受婚前性行为(OR=1.36,95%CI:1.04～1.78)、有家族肿瘤史(OR=1.69,95%CI:1.28～2.23)、月消费水平≥2 000元(OR=1.50,95%CI:1.22～1.84)、知晓HPV疫苗(OR=1.75,95%CI:1.11～2.77)、知晓HPV疫苗已上市(OR=1.71,95%CI:1.44～2.03)、知晓HPV感染与宫颈癌有关(OR=1.44,95%CI:1.15～1.81)、身边有人接种过HPV疫苗(OR=2.23,95%CI:1.66～3.01)、对HPV及其疫苗的认知评分高(OR=1.86,95%CI:1.32～2.62)均是中国高校大学生HPV疫苗接种意愿的促进因素。结论 中国高校大学生HPV疫苗接种意愿率较高，相关防疫部门及卫生机构应加强高校大学生HPV疫苗相关知识的专业普及，并设法完善HPV疫苗接种服务系统和宫颈癌防治服务体系。更多还原

【Abstract】 Objective To systematically evaluate the willingness to receive HPV vaccination and influencing factors among college students in China. Methods Relevant studies were retrieved from PubMed, Embase, Web of Science, The Cochrane Library, CINAHL, PsycINFO, China Biomedical Literature Database, CNKI, Wanfang Database, and VIP Database from the establishment of the databases to March 12, 2025. Meta-analysis was conducted using Stata 17.0 and RevMan 5.4 to assess the willingness to receive HPV vaccination and influencing factors among college students. Results A total of 35 studies involving 62 958 samples were included. The meta-analysis results showed that the willingness rate of college students in China to receive HPV vaccination was 67.0%. Female(OR=3.47, 95%CI: 2.49-4.85), having a history of sexual behavior(OR=1.91, 95%CI: 1.09-3.35), accepting premarital sex(OR=1.36, 95%CI: 1.04-1.78), having a family history of tumors(OR=1.69, 95%CI: 1.28-2.23), monthly consumption level≥2 000 yuan(OR=1.50, 95%CI: 1.22-1.84), knowing about HPV vaccine(OR=1.75, 95%CI: 1.11-2.77), knowing that HPV vaccine is on the market(OR=1.71, 95%CI: 1.44-2.03), knowing that HPV infection is related to cervical cancer(OR=1.44, 95%CI: 1.15-1.81), having someone around who has received HPV vaccine(OR=2.23, 95%CI: 1.66-3.01), and having a high score in the cognition of HPV and its vaccine(OR=1.86, 95%CI: 1.32-2.62) were identified as promoting factors. Conclusion The willingness rate of Chinese college students to receive the HPV vaccine is relatively high, relevant epidemic prevention departments and health institutions should strengthen the professional popularization of HPV vaccine-related knowledge among college students, and try to improve the HPV vaccine vaccination service system and cervical cancer prevention and control service system.更多还原