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基于分子特征的子宫内膜癌保留生育功能诊治中国专家共识(2025版)

Chinese expert consensus on the diagnosis and treatment of endometrial cancer with fertility preservation based on molecular characteristics

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【作者】 陈晓军陈刚刘继红孔北华

【Author】 Chinese Anti-Cancer Association Chinese Uterine Cancer Society;Chinese Society of Gynecologic Oncology,Chinese Medical Association;

【通讯作者】 陈晓军;陈刚;刘继红;孔北华;

【机构】 中国抗癌协会子宫体肿瘤专委会中华医学会妇科肿瘤学分会同济大学附属第十人民医院华中科技大学同济医学院附属同济医院中山大学肿瘤防治中心山东大学齐鲁医院

【摘要】 分子分型在子宫内膜癌保留生育功能诊疗决策中的价值逐步显现。本文整理了分子分型对子宫内膜癌保留生育功能诊疗影响的相关研究,总结了用于子宫内膜癌保留生育功能诊疗的分子分型检测方法和质量控制,不同分子分型的保育适应证和保育治疗方案、完全缓解后预防复发的措施,以及辅助生育治疗方案等方面的循证医学证据,并经专家组反复讨论达成本共识。旨在分子分型的基础上,规范开展子宫内膜癌的保育诊疗实践,不断积累较高质量的临床证据,促进子宫内膜癌保育疗效的不断提升。

【Abstract】 The value of molecular classification in the diagnosis and treatment decision-making for fertility preservation in endometrial cancer has gradually emerged.This article summarizes relevant studies on the impact of molecular classification on the diagnosis and treatment of fertility preservation in endometrial cancer.It consolidates the evidence-based medical data regarding molecular classification detection methods and quality control for fertility preservation treatment in endometrial cancer, indications for fertility preservation across different molecular classifications, fertility preservation treatment protocols, prevention strategies after complete remission, and assisted reproductive treatment plans, leading to the development of this consensus.The aim is to promote the standardized implementation of molecular classification-based diagnosis and treatment for endometrial cancer fertility preservation, continuously accumulate high-quality clinical evidence, and continuously improve the efficacy of fertility preservation in endometrial cancer.

【基金】 国家重点研发计划项目(No:2022YFC2704300);浙江省科技计划“领雁”项目(No:2025C02068)
  • 【文献出处】 现代妇产科进展 ,Progress in Obstetrics and Gynecology , 编辑部邮箱 ,2025年07期
  • 【分类号】R737.33
  • 【下载频次】190
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