【摘要】 目的 了解HIV感染者对猴痘相关知识的知晓情况及其疫苗接种意愿，并分析接种意愿的相关因素。方法 2023年12月至2024年4月，采用方便抽样，在武汉市艾滋病定点医疗机构招募HIV感染者开展问卷调查。调查内容包括社会人口学特征、猴痘相关知识及猴痘疫苗接种意愿。采用χ~2检验分析不同人口学特征调查对象猴痘知识知晓率及猴痘疫苗接种意愿，运用多因素Logistic回归分析影响接种意愿的因素。结果 共纳入463例HIV感染者，猴痘相关知识总体知晓率为27.21%(126/463)，猴痘疫苗接种意愿率为64.36%(298/463)。多因素分析显示，男性（aOR=2.529,95%CI:1.098～5.823）、同性性取向（aOR=2.412,95%CI:1.192～4.881）、非常担心自身感染猴痘（aOR=3.701,95%CI:1.827～7.497）、知晓猴痘相关知识（aOR=2.907,95%CI:1.662～5.085）的感染者更愿意接种猴痘疫苗。结论 武汉市HIV感染者猴痘认知水平和疫苗接种意愿仍有待提高。应通过针对性健康教育和风险沟通提高风险人群对猴痘的认知能力，从而有效降低猴痘在HIV感染者中的传播风险。更多还原

【Abstract】 Objective This study aimed to assess knowledge of Mpox and vaccination willingness among individuals with human immunodeficiency virus(HIV) infection, and to analyze factors influencing vaccination willingness. Methods From December 2023 to April 2024, a questionnaire survey was conducted using convenience sampling among HIV-infected patients attending designated acquired immune deficiency syndrome(AIDS) medical institutions in Wuhan. The survey included sociodemographic characteristics, Mpox knowledge, and vaccination willingness. Chi-square tests were used to examine differences in Mpox knowledge and vaccination willingness across demographic groups. Multivariate logistic regression was performed to identify factors associated with vaccination willingness. Results A total of 463 participants were included. The overall Mpox knowledge rate was 27.21%(126/463), and the vaccination willingness rate was 64.36%(298/463). Multivariate analysis showed that male [adjusted odds ratio(aOR) =2.529, 95% confidence interval(CI): 1.098-5.823], homosexual orientation(a OR=2.412, 95%CI: 1.192-4.881), high concern about Mpox infection(aOR = 3.701, 95%CI: 1.827-7.497), and awareness of Mpox-related knowledge(aOR=2.907, 95%CI: 1.662-5.085) were significantly associated with greater vaccination willingness. Conclusions Mpox awareness and vaccination willingness among HIV-infected individuals in Wuhan remain suboptimal. Targeted health education and risk communication strategies are needed to improve Mpox knowledge among at-risk populations and to mitigate the risk of Mpox transmission in people living with HIV.更多还原