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美托洛尔在心血管疾病治疗中的应用与进展

Application and Progress of Metoprolol in the Treatment of Cardiovascular Diseases

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【作者】 卢天雄; 金亚萍; 沈洁; 吴志瑛; 章塨楠;

【Author】 Lu Tianxiong;Jin Yaping;Shen Jie;Wu Zhiying;Zhang Gongnan;Department of Clinical Pharmacy, the First Affiliated Hospital of Zhejiang University School of Medicine;

【机构】 浙江大学医学院附属第一医院临床药学部;

【摘要】 该文分析美托洛尔的基本药理作用机制,并阐述其在心血管疾病中的具体应用效果,以及新用途的研究进展。美托洛尔是一种选择性β1受体阻滞剂,可降低心率、血压及心肌耗氧量,有效治疗高血压、心绞痛、心肌梗死、心力衰竭、心律失常等心血管疾病。此外,美托洛尔还在治疗甲状腺毒症、预防手术和拔管刺激引起的心动过速和血压升高等方面显示出良好作用。

【Abstract】 This article analyzes the basic pharmacological mechanism of metoprolol and elaborates on its specific application effects in cardiovascular diseases, as well as the research progress of new uses. Metoprolol is a selective beta-1 receptor blocker that can reduce heart rate, blood pressure and myocardial oxygen consumption, and effectively treat cardiovascular diseases such as hypertension, angina pectoris, myocardial infarction, heart failure and arrhythmia. In addition, metoprolol has also shown good effects in the treatment of thyrotoxicosis, preventing tachycardia and elevated blood pressure caused by surgical and extubation stimulation, etc.

  • 【文献出处】 中外医药研究 ,Journal of Chinese and Foreign Medicine and Pharmacy Research , 编辑部邮箱 ,2025年13期
  • 【分类号】R54
  • 【下载频次】18
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