【摘要】 α,β-不饱和醛/酮的选择性加氢通过调控氢物种的传输路径与化学键断裂顺序，选择性还原C=C或C=O键，同时保留分子内的其他官能团，实现对产物结构和性质的精准设计，为高值化分子的定向合成提供关键手段。然而，受限于α,β-不饱和醛/酮中C=O与C=C键的热力学平衡和动力学竞争，其选择性调控极具挑战。因此，构建精准靶向催化体系是突破该反应瓶颈的核心，兼具重要科学价值与工业应用前景。金属有机框架(MOFs)及其衍生物因其拓扑结构可编程性、孔道微环境可调控性、活性位点空间排布可设计性及电子结构可修饰性，为构建精准靶向催化体系提供了创新平台。本文系统综述了近10年MOFs及其衍生物催化剂在α,β-不饱和醛/酮的选择性加氢方面的研究进展，重点分析了催化剂的设计策略、构-效关系及催化机理，旨在为α,β-不饱和醛/酮选择性加氢的靶向催化体系设计提供新思路。更多还原

【Abstract】 The selective hydrogenation of α,β-unsaturated aldehydes/ketones enables precise control over product structures and properties by regulating hydrogen transport pathways and bond cleavage sequences to selectively reduce C=C or C=O bonds while preserving other functional groups within the molecule. This approach serves as a critical strategy for the directional synthesis of high-value molecules. However, achieving such selectivity remains challenging due to the thermodynamic equilibrium and kinetic competition between C=O and C=C bonds in α,β-unsaturated systems. Consequently, constructing precisely targeted catalytic systems is essential to overcome these limitations, offering both fundamental scientific significance and industrial application potential. Metal-organic frameworks(MOFs) and their derivatives have emerged as innovative platforms for designing such systems, owing to their programmable topology, tunable pore microenvironments, spatially controllable active sites, and modifiable electronic structures. This review systematically summarizes the research progress of MOF-based catalysts for selective hydrogenation of α,β-unsaturated aldehydes/ketones in the last decade, with emphasis on the design strategy,conformational relationship, and catalytic mechanism, aiming to provide new ideas for the design of targeted catalytic systems for the selective hydrogenation of α,β-unsaturated aldehydes/ketones.更多还原