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静息态功能磁共振在重复经颅磁刺激治疗卒中后认知障碍中的研究进展

Advances in Resting-state Functional Magnetic Resonance in the Treatment of Post-Stroke Cognitive Impairment with Repetitive Transcranial Magnetic Stimulation

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【作者】 王婷婷; 周立志; 郑苏; 张安东; 李旭英; 彭力;

【Author】 Wang Tingting;Zhou Lizhi;Zheng Su;College of Acupuncture and Orthopedics,Hubei University of Chinese Medicine;Comprehensive Department of Traditional Chinese Medicine and Rehabilitation,Taihe Hospital,Shiyan;Medical Department,Taihe Hospital,Shiyan;

【通讯作者】 彭力;

【机构】 湖北中医药大学针灸骨伤学院; 湖北省十堰市太和医院中医康复综合部; 湖北省十堰市太和医院医务处; 湖北中医药大学附属十堰市中医医院;

【摘要】 卒中后认知障碍是脑卒中患者常见的后遗症,严重影响患者的生活质量和康复进程。重复经颅磁刺激(transcranial magnetic stimulation, rTMS),作为一种新兴的神经调控技术,已广泛应用于卒中后认知障碍的治疗。静息态功能磁共振成像(resting-state functional magnetic resonance imaging, rs-fMRI)作为一种非侵入性神经影像技术,能够揭示大脑在静息状态下的神经网络活动及其连接模式,为研究卒中后认知障碍的神经机制提供了重要手段。该文旨在探讨rs-fMRI在评估rTMS治疗卒中后认知障碍中的研究进展。

【Abstract】 Post-stroke cognitive impairment(PSCI)is a prevalent and debilitating complication of stroke that significantly hinders recovery and diminishes patients’ quality of life.Repetitive transcranial magnetic stimulation(rTMS),a non-invasive neuromodulation technique, has garnered growing interest for its potential to enhance cognitive function in individuals with PSCI.Concurrently, resting-state functional magnetic resonance imaging(rs-fMRI),as a non-invasive neuroimaging technique, has emerged as a valuable tool for assessing spontaneous neural activity and functional connectivity in the brain.By offering insights into the neurobiological mechanisms underlying PSCI and the modulatory effects of rTMS,rs-fMRI provides a foundation for advancing precision-targeted interventions.This review aims to highlight recent progress in applying rs-fMRI to evaluate the efficacy and underlying mechanisms of rTMS in the treatment of PSCI.

【基金】 湖北省中医药科研立项项目(No.ZY2021Q015,No.ZY2019Z-012);十堰市太和医院院级项目(No.2017JJXM094)
  • 【文献出处】 华中科技大学学报(医学版) ,Acta Medicinae Universitatis Scientiae et Technologiae Huazhong , 编辑部邮箱 ,2025年04期
  • 【分类号】R743.3;R445.2
  • 【下载频次】68
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