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鼻咽癌放(化)疗后吞咽功能障碍的影响因素分析

Influencing factor analysis of dysphagia after radio(chemo) therapy for nasopharyngeal carcinoma

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【作者】 张屹邹小量贺广湘夏欣周军校杨枝芳

【Author】 ZHANG Yi;ZOU Xiaoliang;HE Guangxiang;XIA Xin;ZHOU Junxiao;YANG Zhifang;Department of Otolaryngology Head and Neck Surgery,The Central Hospital of Shaoyang;Department of Otolaryngology Head and Neck Surgery,The Third Xiangya Hospital of Central South University;Medical Imaging Center,The Central Hospital of Shaoyang;

【通讯作者】 杨枝芳;

【机构】 邵阳市中心医院耳鼻咽喉头颈外科中南大学湘雅三医院耳鼻咽喉头颈外科邵阳市中心医院医学影像中心

【摘要】 目的 探索鼻咽癌放(化)疗后吞咽功能障碍的影响因素。方法 选取在邵阳市中心医院就诊的鼻咽癌患者37例,评估患者的一般情况、肿瘤相关情况、治疗相关情况,应用吞咽X线荧光透视检查对入组患者进行吞咽功能的评估,采用单因素分析,找出患者吞咽功能障碍的影响因素。结果 单因素分析结果显示,肿瘤分期越高或者采用非调强放疗的患者,吞咽功能障碍的发生率越高。结论 鼻咽癌放(化)疗后吞咽功能障碍的发生可能与肿瘤的分期、放疗的方式有关。

【Abstract】 Objectives To explore the potential factors contributing to dysphagia after radio(chemo) therapy for nasopharyngeal carcinoma. Methods A total of 37 patients diagnosed with nasopharyngeal carcinoma were selected from The Central Hospital of Shaoyang. Comprehensive assessments were performed regarding the patients’ general conditions, tumor characteristics, and treatment modalities. The swallowing function of the enrolled patients was evaluated by video fluoroscopic swallowing study(VFSS), and the influencing factors of dysphagia were identified via univariate analysis. Results Univariate analysis revealed that the incidence of dysphagia was higher in patients with advanced tumor stages or those receiving non-intensive-modulated radiotherapy. Conclusion The occurrence of dysphagia after radio(chemo)therapy for nasopharyngeal carcinoma may be related to the tumor stage and the type of radiotherapy administered.

【基金】 湖南省技术创新引导计划-临床医疗技术创新引导项目(2018SK51808);邵阳市科技计划项目(2015GX56)
  • 【文献出处】 邵阳学院学报(自然科学版) ,Journal of Shaoyang University(Natural Science Edition) , 编辑部邮箱 ,2025年01期
  • 【分类号】R739.63
  • 【下载频次】40
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