【摘要】 银屑病关节炎（PsA）是一种与银屑病密切相关的慢性全身炎症性疾病，其临床表现复杂多样，在我国诊断延迟、治疗不规范现象普遍存在，严重影响患者预后。近年来早期银屑病关节炎筛查问卷（EARP）、银屑病流行病学筛查工具问卷（PEST）等筛查问卷为早期PsA患者筛选提供了新的思路。此外，特殊部位银屑疹、指甲病变以及肌腱附着点、指（趾）炎等骨骼肌肉症状有助于识别PsA高风险人群，生物标志物、MRI及肌骨超声的应用可辅助鉴别类风湿关节炎（RA）、强直性脊柱炎（AS）等其他炎性关节炎，从而实现PsA的早期诊断和及时干预，以达到降低疾病致残率，提高患者生活质量的目标。更多还原

【Abstract】 Psoriatic arthritis(PsA),which is closely linked to psoriasis,is a chronic systemic inflammatory disease characterized by complex and heterogeneous manifestations. In China,delayed diagnosis and suboptimal treatment are prevalent,significantly affecting the prognosis of patients. In recent years,standardized screening questionnaires such as EARP and PEST have provided new insights for the identification of early PsA patients. Furthermore,psoriasis in special areas,nail lesions,as well as musculoskeletal symptoms like enthesitis and dactylitis are helpful in recognizing high-risk populations of PsA. The use of biomarkers,MRI and musculoskeletal ultrasound can assist in differentiating PsA from other inflammatory arthritis including rheumatoid arthritis(RA)and ankylosing spondylitis(AS),so that early diagnosis and timely intervention of PsA can be achieved,which effectively reduces disease-related disability and improve patients’ quality of life.更多还原