【摘要】 目的：研究运动零食对久坐成年人、血糖、胰岛素和甘油三酯的影响效果，提出中断久坐行为的运动零食最佳方案。方法：运用Review Manager 5.4对纳入的16篇文献进行Meta分析，采用随机效应模型对运动强度、单次运动时长、运动方式进行亚组分析。结果：与对照组相比，运动零食对餐后血糖的影响有显著效果，SMD为-0.38(95%CI:[-0.70,-0.07],P=0.02,I~2=0%);自重练习SMD为-0.61 (95%CI:[-0.90,-0.32],P<0.0001,I~2=0%)和≤5 min的运动时间SMD为-0.45 (95%CI:[-0.68,-0.21],P<0.001,I~2=1%)对餐后血糖AUC影响效果显著；运动零食对胰岛素AUC的影响有显著效果，SMD为-0.33(95%CI:[-0.55,-0.11],P=0.003,I~2=0%)。其中，≤5min的运动零食与对照组相比，对胰岛素AUC的影响显著，SMD为-0.31(95%CI:[-0.56,-0.05],P=0.002,I~2=0%);运动零食对甘油三酯AUC的影响不具有显著性，SMD为0.03(95%CI:[-0.20,0.25],P=0.82,I~2=0%)。结论：通过运动零食来中断长时间的久坐行为，有助于消除久坐人群的一些有害代谢影响；运动零食可短暂改善餐后血糖和胰岛素水平，但没有观察到甘油三酯的差异。建议：采用≤5 min的锻炼时长，锻炼方式可采用自重练习或爬楼梯；由于长期干预研究数量有限，偏倚风险各不相同，因此难以得出任何长期影响的结论。更多还原

【Abstract】 This paper aims to evaluate the effectiveness of exercise snacks on the blood glucose, insulin, and triglycerides of sedentary adults, and to propose an optimal regimen of exercise snacks for interrupting sedentary behavior.Methods: Review Manager 5.4 was utilized to conduct a meta-analysis of 16 included studies.Subgroup analyses were performed using a random-effects model for exercise intensity, duration of single exercise bouts, and type of exercise.Results: Compared to the control group, exercise snacks have a significant effect on postprandial blood glucose with an SMD of-0.38(95% CI:[-0.70,-0.07],P=0.02,I~2=0%).Bodyweight exercises have an SMD of-0.61(95% CI:[-0.90,-0.32],P<0.0001,I~2=0%),and exercise duration of ≤5 minutes has an SMD of-0.45(95% CI:[-0.68,-0.21],P<0.001,I~2=1%),showing a significant effect on postprandial blood glucose AUC.Exercise snacks have a significant effect on insulin AUC with an SMD of-0.33(95% CI:[-0.55,-0.11],P=0.003,I~2=0%).Among these, exercise snacks with a duration of ≤5 minutes have a significant effect on insulin AUC compared to the control group, with an SMD of-0.31(95% CI:[-0.56,-0.05],P=0.002,I~2=0%).However, exercise snacks do not have a significant effect on triglyceride AUC,with an SMD of 0.03(95% CI:[-0.20,0.25],P=0.82,I~2=0%).Conclusion: Interrupting prolonged sedentary behavior with exercise snacks helps mitigate some adverse metabolic effects in sedentary individuals.Exercise snacks can transiently improve postprandial glucose and insulin levels, but no difference was observed in triglyceride levels.It is recommended to use exercise bouts of ≤5 minutes, with exercises such as bodyweight exercises or stair climbing.Due to the limited number of long-term intervention studies and varying risks of bias, it is difficult to draw conclusions regarding long-term effects.更多还原