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基于脏腑理论分期辨证施治肌萎缩侧索硬化症

Staged syndrome differentiation and treatment for amyotrophic lateral sclerosis based on visceral theory

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【作者】 单悦童吴菲菲梁星旺荆玮张海涵李威潘卫东

【Author】 SHAN Yuetong;WU Feifei;LIANG Xingwang;JING Wei;ZHANG Haihan;LI Wei;PAN Weidong;Department of Neurology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;Department of Neurology, Gongli Hospital,Pudong New Area;Shanghai Shengsijia Nursing Home;

【通讯作者】 潘卫东;

【机构】 上海中医药大学附属曙光医院脑病科上海市浦东新区公利医院神经内科上海胜似家护理院

【摘要】 肌萎缩侧索硬化症(ALS)是最常见的运动神经元病(MND),目前西医治疗药物的种类较少,疗效欠佳。中医治疗可针对不同临床分期患者,辨证施治,延缓病情进展。以中医脏腑理论为基础,探讨ALS的中医病因病机及不同疾病分期的证型分布特点,认为脾肾亏虚证贯穿疾病各期,肝肾亏虚证多见于疾病中晚期,脾肺肾亏虚证常见于疾病终末期,针对不同分期辨证施治,为中医药治疗ALS提供参考。

【Abstract】 Amyotrophic lateral sclerosis(ALS) is the most common motor neuron disease(MND). At present, there are few types of western medicine treatment drugs with poor efficacy. Traditional Chinese medicine(TCM) treatment can target patients with different clinical stages of the disease, and delay the progression of the disease through syndrome differentiation and treatment. Based on the visceral theory of TCM, this paper explores the TCM etiology and pathogenesis of ALS, and the distribution characteristics of syndrome types in different stages of ALS. It is believed that spleen and kidney deficiency syndrome runs through all stages of the disease, liver and kidney deficiency syndrome is more common in the middle and late stages of ALS, while spleen, lung and kidney deficiency syndrome is common in the end-stage of the disease. Syndrome differentiation and treatment according to different stages can provide a reference for the treatment of ALS with TCM.

【基金】 上海市浦东新区卫健委卫生计生科研项目(PW2022E-03);上海市科委2024年度科技创新行动计划医学创新研究领域项目(24Y12800900)
  • 【文献出处】 上海中医药大学学报 ,Academic Journal of Shanghai University of Traditional Chinese Medicine , 编辑部邮箱 ,2025年02期
  • 【分类号】R277.7
  • 【下载频次】23
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