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基于时间序列和KA-Transformer 模型的早期脓毒症预测

Early sepsis prediction based on time series and KA-Transformer models

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【作者】 朱宇张天逸张立程云章

【Author】 ZHU Yu;ZHANG Tianyi;ZHANG Li;CHENG Yunzhang;School of Health Science and Engineering,University of Shanghai for Science and Technology;Shanghai Interventional Medical Device Engineering Technology Research Center;Department of Cardiothoracic Surgery,The Second Affiliated Hospital of Naval Medical University;School of Medicine,Tongji University;

【通讯作者】 程云章;

【机构】 上海理工大学健康科学与工程学院上海介入医疗器械工程技术研究中心海军军医大学第二附属医院胸心外科同济大学医学院

【摘要】 为实现对脓毒症的提前预测,本研究设计了一种基于时间序列数据的预测模型KA-Transformer。通过在KA-Transformer中引入核注意力机制,以改善训练样本有限、参数众多及样本分布不均等问题。将连续的时间序列数据输入模型,结果显示:在脓毒症发生前1、6和12 h的3个预测时间点,模型预测脓毒症的受试者工作特征曲线下面积分别为0.962、0.944和0.984,准确率分别为92.3%、93.9%和96.1%。实验结果表明,KA-Transformer在脓毒症预测的准确性和泛化能力方面优于现有方法,在提升脓毒症预测实时性与可靠性方面具备一定潜力。

【Abstract】 To achieve early prediction of sepsis, we designed a prediction model KA-Transformer based on time series data. A kernel attention mechanism was introduced in the KA-Transformer to improve issues such as limited training samples, numerous parameters, and uneven sample distribution. With the input of continuous time series data, at three prediction time points 1,6,and 12 h before sepsis onset, the area under the receiver operating characteristic curve of the model for predicting sepsis were 0.962, 0.944 and 0.984, respectively, the accuracy rates were 92.3%, 93.9% and 96.1%, respectively. The experimental results show that the KA-Transformer significantly outperforms existing methods in terms of accuracy and generalization ability for sepsis prediction, and has the potential to enhance the timeliness and reliability of prediction for sepsis prediction.

  • 【文献出处】 生物医学工程研究 ,Journal of Biomedical Engineering Research , 编辑部邮箱 ,2025年02期
  • 【分类号】R459.7;O211.61
  • 【下载频次】9
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