【摘要】 创伤后应激障碍（PTSD）是一种暴露于严重创伤性事件之后的精神障碍，其主要临床症状包括侵入性记忆、回避提醒、负面情绪、高警觉性等。大量研究显示，神经炎症可能是PTSD发病的关键因素，PTSD模型动物的相应脑区在应激后显示出炎性标志物的表达异常。中医药疗法具有多途径、多靶点的干预特点，在PTSD的治疗中具有一定优势，多种中医药疗法被报道能够干预PTSD神经炎症，但尚未有文献能厘清其具体的干预效应和抗炎机制。基于此，本文对中医药干预PTSD的现有研究进行综述，并从中医药种类、抗炎机制、抗炎作用、动物模型、脑区等维度，重点阐释中医药干预PTSD的现状与进展，以期为PTSD的临床治疗策略提供借鉴与参考。更多还原

【Abstract】 Post-traumatic stress disorder(PTSD) is a mental disorder after exposure to a severe traumatic event, and its main clinical symptoms include intrusive memory, avoidance of reminders, negative emotions, and hypervigilance. Numerous studies have shown that neuroinflammation may be a key factor in the pathogenesis of PTSD, with corresponding brain regions of PTSD model animals showing abnormal expression of inflammatory markers after stress. Traditional Chinese medicine(TCM) therapies have been reported to be able to intervene in the neuroinflammation of PTSD, but there is no literature to clarify their specific intervention effects and anti-inflammatory mechanisms. Based on this, this article provides a review of the existing research on the intervention of TCM in PTSD, and focuses on the current situation and progress of TCM intervention in PTSD from the dimensions of TCM types, anti-inflammatory mechanisms, anti-inflammatory effects, animal models, and brain regions, in order to provide reference for the clinical treatment strategy of PTSD.更多还原