节点文献

中医湿证评估量表在特应性皮炎患者的适用性评价

Evaluation of the Applicability of the Dampness Syndrome Scale of Chinese Medicine (DSSCM) in Patients with Atopic Dermatitis

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 朱骊安钟柳张瑜叶思祺莫秀梅

【Author】 ZHU Li’an;ZHONG Liu;ZHANG Yu;YE Siqi;MO Xiumei;The Second School of Clinical Medicine,Guangzhou University of Chinese Medicine;Provincial-Ministry Jointly Established State Key Laboratory of Dampness Syndrome in Traditional Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Chinese Medicine);Dept. of Dermatology,Guangdong Provincial Hospital of Chinese Medicine;

【通讯作者】 莫秀梅;

【机构】 广州中医药大学第二临床医学院省部共建中医湿证国家重点实验室(广州中医药大学第二附属医院)广东省中医院皮肤科

【摘要】 【目的】评价中医湿证评估量表(DSSCM)应用于特应性皮炎患者的适用性。【方法】采用横断面调查法,采集204例特应性皮炎患者的基本信息以及DSSCM、患者湿疹自我检查评分量表(POEM)、特应性皮炎控制工具(ADCT)、特应性皮炎积分指数(SCORAD)、湿疹面积及严重程度指数(EASI)、研究者总体评估(IGA)量表的得分情况,使用SPSS、AMOS分析DSSCM的信度和效度,探究湿证与特应性皮炎临床指标间的相关性。【结果】量表总体克朗巴赫α系数(Cronbach’α系数)为0.90,Spearman-Brown分半信度系数为0.81,内容效度结果除外DSSCM 25、DSSCM 26、DSSCM 27、DSSCM 28、DSSCM 29这5个条目的系数范围<0.30,其余各条目与维度以及维度与量表总分间的相关系数范围均大于0.40。集合效度、区分效度实验成功率均大于80%,验证性因子分析中卡方自由度比(χ2/df)、近似平均方根误差(RMSEA)达到良好标准。相关性分析结果显示,DSSCM评分与体质量指数(BMI)、皮肤病生活质量指数(DLQI)得分、POEM得分、ADCT得分、瘙痒得分、睡眠得分、SCORAD得分均显著相关(P<0.05或P<0.01),与病程、年龄、IGA得分、EASI得分均无显著性相关(P>0.05)。【结论】DSSCM应用于特应性皮炎患者具有良好的信度和效度,与特应性皮炎临床指标间具有相关性,适用于特应性皮炎患者临床湿证评估。

【Abstract】 Objective To evaluate the applicability of the Dampness Syndrome Scale of Chinese Medicine(DSSCM) in patients with atopic dermatitis(AD). Methods A cross-sectional study was conducted 204 AD patients. Demographic data and scores of the DSSCM, Patient-Oriented Eczema Measure(POEM), Atopic Dermatitis Control Tool(ADCT),Scoring Atopic Dermatitis(SCORAD),Eczema Area and Severity Index(EASI),and Investigator’s Global Assessment(IGA) were collected. SPSS and AMOS were used to analyze the reliability and validity of the DSSCM and then the correlation between dampness syndrome and clinical AD indicators was explored. Results The overall Cronbach’s α coefficient of DSSCM was 0.90,and the Spearman-Brown split-half reliability coefficient was 0.81. Content validity results indicated that,except for items DSSCM 25,DSSCM 26,DSSCM 27, DSSCM 28, and DSSCM 29(with correlation coefficients <0.30), all other items showed correlation coefficients >0.40 with their respective dimensions and the total scale score. The success rates of convergent and discriminant validity tests exceeded 80%,and confirmatory factor analysis demonstrated good fit in the indices of χ~2/df and RMSEA. Correlation analysis revealed that DSSCM scores were significantly correlated with body mass index(BMI),Dermatology Life Quality Index(DLQI) scores,POEM scores,ADCT scores,pruritus scores, sleep scores, or SCORAD scores(P<0.05 or P<0.01). However, no significant correlations were observed between DSSCM scores and disease duration,age,IGA scores,or EASI scores(P>0.05). Conclusion The DSSCM demonstrates good reliability and validity in AD patients and its scores are correlated with clinical AD indicators,making it a suitable tool for assessing dampness syndrome in this population.

【基金】 省部共建中医湿证国家重点实验室重点项目(编号:SZ2021ZZ39);广东省重点领域研发计划项目(编号:2020B1111100010)
  • 【文献出处】 广州中医药大学学报 ,Journal of Guangzhou University of Traditional Chinese Medicine , 编辑部邮箱 ,2025年10期
  • 【分类号】R275.9
  • 【下载频次】65
节点文献中: 

本文链接的文献网络图示:

本文的引文网络