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复方黄柏液涂剂对低位肛瘘湿热下注证术后创面愈合的影响

Effect of Compound Huangboye Liniment on Postoperative Wound Healing of Low Anal Fistula with Downward Attack of Damp-Heat Syndrome

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【作者】 许嘉纯杨巍

【Author】 XU Jiachun;YANG Wei;Department of Proctology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;

【通讯作者】 杨巍;

【机构】 上海中医药大学附属曙光医院肛肠科

【摘要】 目的:观察复方黄柏液涂剂对低位肛瘘湿热下注证术患者后创面愈合的影响。方法:选取2023年3—10月上海中医药大学附属曙光医院肛肠科接受肛门瘘管切除术的低位肛瘘湿热下注证患者120例,按随机数字表法分为试验组和对照组各60例。试验过程中每组各脱落2例。对照组采用康复新液进行术后创面换药,试验组采用复方黄柏液涂剂进行术后创面换药。评价2组临床疗效,比较2组创面愈合率、创面疼痛程度、创面瘙痒评分。结果:经过秩和检验,试验组整体疗效优于对照组,差异有统计学意义(P<0.05)。试验组术后第28天创面愈合率高于对照组,差异有统计学意义(P<0.05)。术后第7、14、21天,试验组创面视觉模拟评分法(VAS)评分、创面瘙痒评分均低于对照组,差异均有统计学意义(P<0.05)。结论:复方黄柏液涂剂湿敷治疗低位肛瘘湿热下注证术后患者能提高创面愈合率,缓解术后创面疼痛、瘙痒,提高临床疗效。

【Abstract】 Objective:To observe the effeet of Compound Huangboye Liniment on postoperative wound healing oflow anal fistula with downward attack of damp-heat syndrome patients.Methods:A total of 120 patients with low analfistula with downward attack of damp-heat syndrome who underwent anal fistulectomy in the Department of Proctology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,were selected from March 2023 toOctober 2023,and were divided into 60 cases each in the trial group and the control group according to the randomnumber table method.During the experiment, two cases fell off in each group. The control group received KangfuxinLiquid for postoperative wound dressing,and the trial group received Compound Huangboye Liniment for postoperativewound dressing. The clinical efficacy of the two groups was evaluated,and the wound healing rate,wound pain severity,and wound itching score of the two groups were compared.Results:After the rank sum test,the overall efficacy of thetrial group was superior to that of the control group,the difference being significant(P<0.05). The wound healing rate ofthe trial group was higher than that of the control group on the 28th postoperative day,the difference being significant(P<0.05). On the 7th, 14th, and 21st, postoperative days, the wound Visual Analogue Scale(VAS)score and wounditching score of the trial group were lower than those of the control group, differences being significant(P<0.05).Conclusion:Wet compress of Compound Huangboye Liniment for postoperative patients with low anal fistula withdownward attack of damp-heat syndrome can improve the wound healing rate, relieve postoperative wound pain,wound itching,and enhance the clinical efficacy.

【基金】 上海市科学技术委员会项目(22Y11922300)
  • 【分类号】R266
  • 【下载频次】28
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