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血栓弹力图与凝血四项、血小板计数在胃恶性肿瘤患者中的相关性分析
Analysis of correlation between thromboelastogram and four coagulation tests and platelet count in patients with gastric malignant tumor
【摘要】 目的 分析血栓弹力图、凝血四项、血小板计数在胃恶性肿瘤患者中相关性及一致性。方法 回顾性分析2022—2023年本院初治并同时间进行血栓弹力图、凝血四项、血小板计数检测的159例胃恶性肿瘤患者的临床资料,比较其对高凝状态的预测价值,并进行相关性及一致性分析。结果 TEG对提示胃恶性肿瘤患者的高凝状态的价值优于凝血四项与血小板计数(P<0.001)。R与PT和APTT无显著相关性,与TT呈正相关;K与PLT和FIB呈负相关,与TT呈正相关;Angle、MA与TT呈负相关,与PLT和FIB呈正相关。PT、APTT与TEG各指标均无一致性,R与TT一致性为极差,K、Angle、MA分别与PLT、FIB的一致性均为弱。结论 TEG对提示胃恶性肿瘤患者的高凝状态优于凝血四项与血小板计数,TEG与凝血四项、血小板计数有一定的相关性,但一致性差。临床应根据患者具体情况,结合临床需求来优化组合检测项目,为胃恶性肿瘤患者的临床治疗提供实验室依据。
【Abstract】 Objective To analyze the correlation and consistency of thromboelastogram, four coagulation tests and platelet count in patients with gastric malignant tumors.Methods The clinical data of 159 patients with gastric malignancies who were initially treated at our hospital and underwent thromboelastography, four coagulation tests, and platelet count testing simultaneously between 2022 and 2023 were retrospectively analyzed. The predictive value for hypercoagulable status was compared, and correlation and consistency analyses were performed.Results The value of thromboelastogram(TEG) in indicating hypercoagulable status in patients with gastric malignancies was superior to that of the four coagulation tests and platelet count(P<0.001). R had no significant correlation with PT and APTT but was positively correlated with TT. K had a negative correlation with PLT and FIB and a positive correlation with TT. Angle and MA had a negative correlation with TT and a positive correlation with PLT and FIB. There was no concordance between PT, APTT, and TEG indices. The concordance between R and TT was extremely poor, while the consistency between K, Angle, and MA with PLT and FIB was weak.Conclusions TEG is better than the four coagulation tests and platelet count in suggesting hypercoagulable state in patients with gastric malignancy. TEG had a certain correlation with the four coagulation tests and platelet count, but the consistency was poor. Clinics should optimize the combination of testing items according to the specific conditions of patients and clinical needs to provide a laboratory basis for the clinical treatment of patients with gastric malignant tumors.
【Key words】 Gastric malignancy; Thromboelastogram; Four coagulation tests; Platelet; Hypercoagulation; Correlation; Consistency;
- 【文献出处】 齐齐哈尔医学院学报 ,Journal of Qiqihar Medical University , 编辑部邮箱 ,2025年06期
- 【分类号】R735.2
- 【下载频次】69