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水凝胶伤口敷料用于伤口创面愈合的研究进展
Progress of hydrogel wound dressing for wound healing
【摘要】 目的 伤口创面长期不愈合会导致伤口部位受细菌的侵袭、微生物的感染甚至人体代谢紊乱等一系列严重的症状。因此,良好的伤口敷料对伤口愈合是至关重要的,它能够在伤口表面和外部环境之间提供保护屏障,防止再受侵害。基于此,笔者综述了水凝胶伤口敷料在治疗伤口创面愈合的优势(3D结构、良好的生物相容性、优异的渗透性等)以及不同类型的水凝胶敷料促进创面愈合的研究进展,期望为水凝胶伤口敷料的后续研究提供参考。方法 查阅国内外近年来关于水凝胶伤口敷料的相关文献,总结了不同类型的水凝胶敷料对伤口愈合的一些研究进展和自身治疗创伤所具备的优势。结论 基于水凝胶体系的伤口敷料不仅在创面愈合领域有很大的应用前景,而且在临床和生物医学范畴也有潜在的探索性。
【Abstract】 Purpose Long term non healing of wounds can lead to a series of serious symptoms such as bacterial invasion, microbial infection, and even metabolic disorders in the human body. Therefore, good wound dressings are crucial for wound healing. They can provide a protective barrier between the wound surface and the external environment to prevent further damage. Based on this, the advantages of hydrogel wound dressings in the treatment of wound healing(3D structure, good biocompatibility, excellent permeability, etc.) and the research progress of different types of hydrogel dressings in promoting wound healing were reviewed, hoping to provide reference for the follow-up research of hydrogel wound dressings. Method The relevant literatures on hydrogel wound dressings at home and abroad in recent years were reviewed, and the research progress of different types of hydrogel dressings on wound healing and the advantages of self-treatment of wounds were summarized. Conclusion The wound dressings based on hydrogel system not only have great application prospects in the field of wound healing, but also have potential exploration in clinical and biomedical fields.
【Key words】 hydrogel wound dressing; wound healing; crosslinked hydrogel; natural polymer materials; responsiveness;
- 【文献出处】 中国药剂学杂志(网络版) ,Chinese Journal of Pharmaceutics(Online Edition) , 编辑部邮箱 ,2025年01期
- 【分类号】TQ427.26;R318.08;R641
- 【下载频次】415