【摘要】 目的 调查低年级男大学生膀胱过度活动症(OAB)发生的相关影响因素，并分析OAB对患者群体心理健康、生活质量及社会交往的影响。方法 采取匿名的方式对2023—2024年新乡医学院和新乡医学院三全学院两所高校5300名新入学男大学生(17～22岁)OAB的患病率进行流行病学问卷调查，问卷内容包括基本信息、尿路感染史、便秘、吸烟史、饮酒史、饮咖啡/浓茶史、饮碳酸饮料史、包皮过长、包茎、憋尿、慢性失眠、焦虑自评量表(SAS)、生活质量评分(QoL)、社交回避及苦恼量表(SADS)。采用logistic回归分析低年级男大学生OAB发生的相关影响因素。根据是否患有OAB将调查对象分组，比较OAB组与非OAB组间SAS、QoL及SADS评分差异。采用多重线性回归分析OAB对调查对象焦虑程度、生活质量及社会交往的影响。结果 低年级男大学生OAB的总体患病率为4.9%(244/5018)。多因素logistic回归分析显示尿路感染史(OR=0.177)、便秘(OR=0.636)、吸烟史(OR=0.582)、饮酒史(OR=0.685)、饮咖啡/浓茶史(OR=0.387)、饮碳酸饮料史(OR=0.631)、包皮过长(OR=0.673)、包茎(OR=0.311)、憋尿(OR=0.593)、慢性失眠(OR=0.256)是低年级男大学生OAB发生的相关影响因素(P<0.05)。OAB组与非OAB组的SAS评分[(41.18±6.54)分vs.(38.61±6.36)分]、QoL评分[(3.65±1.20)分vs.(2.79±0.95)分]、社交回避评分[(6.25±1.86)分vs.(5.86±1.51)分]、社交苦恼评分[(6.27±1.59)分vs.(5.97±1.32)分]和SADS总分[12.51±2.35)分vs.(11.84±2.01)分]比较，OAB组均更高(P<0.05)。多重线性回归分析结果显示，OAB可独立影响QoL、SAS和SADS评分，OAB组比非OAB组更容易引起QoL、SAS和SADS评分增加(P<0.001)。结论 尿路感染史、便秘、吸烟史、饮酒史、饮咖啡/浓茶史、饮碳酸饮料史、包皮过长、包茎、憋尿及慢性失眠是低年级男大学生OAB发生的相关影响因素，并且OAB对患病群体心理健康、生活质量和社会交往有负面影响。更多还原

【Abstract】 Objective To investigate the influencing factors of overactive bladder(OAB) in college freshmen and the impacts of OAB on their mental health, quality of life and social interaction.Methods An epidemiological questionnaire survey was conducted in an anonymous manner on the prevalence of OAB among 5300 freshmen aged 17 to 22 years enrolled in the 2023—2024 academic year in Xinxiang Medical University and Sanquan College of Xinxiang Medical University.The questionnaire included questions on basic information, history of urinary tract infection, constipation, smoking, history of alcohol consumption, history of coffee/strong tea drinking, history of carbonated beverage drinking, redundant prepuce, phimosis, holding urine, chronic insomnia, self-rating anxiety scale(SAS),quality of life score(QoL),and social avoidance and distress scale(SADS).The influencing factors of OAB were analyzed with multivariate logistic regression analysis.The subjects were grouped according to whether they had OAB,and the differences in SAS,QoL and SADS between the OAB group and non-OAB group were compared.The impacts of OAB on the anxiety level, quality of life, and social interaction were analyzed with multiple linear regression analysis.Results The overall prevalence rate of OAB was 4.9%(244/5018).Multivariate logistic regression analysis showed that the history of urinary tract infection(OR=0.177),constipation(OR=0.636),smoking(OR=0.582),alcohol consumption(OR=0.685),coffee/strong tea drinking(OR=0.387),carbonated beverage drinking(OR=0.631),redundant prepuce(OR=0.673),phimosis(OR=0.311),urine holding(OR=0.593),and chronic insomnia(OR=0.256) were influencing factors for the occurrence of OAB(P<0.05).The OAB group had higher SAS score [(41.18±6.54) vs.(38.61±6.36)],QoL score [(3.65±1.20) vs.(2.79±0.95)],social avoidance score [(6.25±1.86) vs.(5.86±1.51)],social distress score [(6.27±1.59) vs.(5.97±1.32)],and total SADS score [(12.51±2.35) vs.(11.84±2.01)] than the non-OAB group(P<0.05).The results of multiple linear regression analysis showed that OAB could independently affect the scores of QoL,SAS,and SADS.The OAB group had higher scores of QoL,SAS,and SADS compared with the non-OAB group(P<0.001).Conclusion History of urinary tract infection, constipation, smoking, alcohol consumption, coffee/strong tea drinking, carbonated beverage drinking, redundant prepuce, phimosis, urine holding, and chronic insomnia are influencing factors for the occurrence of OAB in male college students.Moreover, OAB has negative impacts on their mental health, quality of life, and social interaction.更多还原