【摘要】 反应性血管内皮瘤病是一种罕见的良性反应性血管增生性疾病，本文报道一例。患者，男，63岁。胸腹部紫红斑伴瘙痒1年，泛发全身1个月。皮损组织病理：角化过度，真皮浅中层毛细血管及内皮细胞增生，多数管腔内可见纤维蛋白血栓。诊断：反应性血管内皮瘤病。入院后给予患者甲泼尼龙16 mg每日1次及环磷酰胺50 mg每日1次治疗，3天后患者皮损较前好转出院，出院后患者口服醋酸泼尼松20 mg每日1次治疗，逐渐减量至2.5 mg每日1次，共服用2年。现患者停药1年，皮疹基本消退，无新发皮疹。更多还原

【Abstract】 Reactive angioendotheliomatosis is a rare benign reactive vascular proliferative disorder. We report the case of a 63-year-old man who presented with violaceous red patches on the chest and abdomen, accompanied by pruritus for one year, which became generalized over one month. Histopathological examination of the skin lesions revealed hyperkeratosis, proliferation of capillaries and endothelial cells in the superficial and middle dermis, and fibrin thrombi in most vascular lumens. A diagnosis of reactive angioendotheliomatosis was made. Following admission, the patient was administered methylprednisolone(16 mg daily) and cyclophosphamide(50 mg daily). After three days, the skin lesions showed improvement, and the patient was discharged. Post-discharge, he was prescribed oral prednisone acetate(20 mg daily), which was gradually tapered to 2.5 mg daily over a total treatment period of two years. At the most recent follow-up(one year after discontinuation of medication), the rash had largely resolved with no new lesions.更多还原