【摘要】 目的 测量输尿管结石及肾积液的CT值，检测外周血炎性标志物，评估这些指标对尿路感染的预测价值，为临床诊治提供依据。方法 收集2021年3月～2024年2月本院120例输尿管结石合并肾积液患者，分为病例组(感染组)52例和对照组(无感染组)68例。检测患者血常规(WBC、N%)、C反应蛋白(C-reactive protein, CRP)、白细胞介素6(interleukin-6,IL-6)、降钙素原(procalcitonin, PCT)等指标，测量肾积液及输尿管结石CT值。采用SPSS 27.0进行统计分析，比较两组差异，评估各指标对感染的预测价值。结果 单因素分析显示，病例组与对照组在性别、肾积液CT值、WBC、N%、CRP、PCT、IL-6水平上差异显著(P<0.05)。多因素Logistic回归分析表明，肾积液CT值是判断感染的独立相关因素(P<0.05),特异性优于其他指标。ROC曲线分析显示，肾积液CT值、WBC、N%、CRP、PCT、IL-6水平与感染风险呈正相关(P<0.05)。结论 女性输尿管结石合并肾积液患者更易发生感染，肾积液CT值、WBC、N%、CRP、PCT、IL-6水平对感染预测具有较高价值，而输尿管结石CT值不能单独作为感染预测指标。更多还原

【Abstract】 Objective To assess the predictive significance of CT values of ureteral stones and hydronephrosis, along with peripheral blood inflammatory markers, in the diagnosis of urinary tract infections(UTIs),thereby providing a foundation for clinical diagnosis and treatment.Methods A total of 120 patients with ureteral stones and hydronephrosis, who were admitted to our hospital from March 2021 to February 2024,were recruited.These patients were classified into an infection group(n=52) and a no-infection group(n=68).Parameters such as body temperature, white blood cell count(WBC),neutrophil percentage(N%),C-reactive protein(CRP),interleukin-6(IL-6),and procalcitonin(PCT) were recorded.The CT values of hydronephrosis and ureteral stones were measured.Statistical analysis was conducted using SPSS 27.0 to compare the differences between the two groups and evaluate the predictive value of each indicator for infection.Results Univariate analysis demonstrated significant differences between the infection and non-infection groups in terms of gender, the CT value of hydronephrosis, WBC,N%,CRP,PCT,and IL-6 levels(P<0.05).Multivariate logistic regression analysis indicated that the CT value of hydronephrosis was an independent factor for predicting infection(P<0.05),with a higher specificity compared to other indicators.Receiver operating characteristic(ROC) curve analysis revealed that the CT value of hydronephrosis, WBC,N%,CRP,PCT,and IL-6 levels were positively associated with the risk of infection(P<0.05).Conclusion Female patients with ureteral stones and hydronephrosis are more susceptible to infection.The CT value of hydronephrosis, along with WBC,N%,CRP,PCT,and IL-6 levels, exhibits a high predictive value for infection.In contrast, the CT value of ureteral stones alone cannot be regarded as a reliable predictor.更多还原