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关注稳定期慢性阻塞性肺疾病治疗药物可及性

Focus on the Availability of Drugs for Stable COPD

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【作者】 申永春; 秦江月; 杜东儒; 胥馨尹; 陈磊; 文富强;

【Author】 SHEN Yongchun;QIN Jiangyue;DU Dongru;XU Xinyin;CHEN Lei;WEN Fuqiang;Department of Pulmonary and Critical Care Medicine, West China Hospital of Sichuan University;Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China;General Practice Ward/International Medical Center Ward, General Practice Medical Center, West China Hospital, Sichuan University;Institute of Non-Communicable Chronic Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention;

【机构】 四川大学华西医院呼吸与危重症医学科; 生物治疗国家重点实验室呼吸病学研究室; 四川大学华西医院全科医学中心; 四川省疾病预防控制中心慢性非传染性疾病预防控制所;

【摘要】 药物治疗是稳定期慢性阻塞性肺疾病的重要干预措施,有效的药物干预可显著改善慢性阻塞性肺疾病患者的临床症状和生活质量,还能降低急性加重风险。但是目前世界范围内面临着经济发展欠均衡、医疗投入不足、药物费用偏高等困难,导致慢性阻塞性肺疾病稳定期治疗药物的可及性存在挑战,如慢性阻塞性肺疾病药物尤其是吸入性药物配备不足、不同等级医疗机构之间慢性阻塞性肺疾病药物配置差异大等一系列问题,进而影响慢性阻塞性肺疾病的规范化治疗。本文就稳定期慢性阻塞性肺疾病治疗药物可及性的国内外研究进展作一述评,拟为慢性阻塞性肺疾病的管理提供更多临床证据。

【Abstract】 Drug therapy is an important intervention for stable chronic obstructive pulmonary disease(COPD). Effective drug therapy can significantly improve the clinical symptoms and quality of life, and reduce the risk of acute exacerbation. However, the world is currently facing difficulties such as uneven economic development, insufficient investment inmedical care, and high drug costs, which pose challenges to the availability of drugs for COPD. There are a series of problems, such as in sufficient supply of drugs for COPD, especially inhaled drugs, and significant differences in drug configuration among different levels of medical institutions, which in turn affect the standardized treatment. This article systematically summarized the research progress on the availability of drugs for the treatment of stable COPD at home and abroad, attempting to provide more clinic evidence for the management of COPD.

【基金】 国家自然科学基金(82170046,31871157);华西医院1·3·5工程项目(RHM24207);四川省科技厅项目(2024NSFSC1522)
  • 【文献出处】 西南医科大学学报 ,Journal of Southwest Medical University , 编辑部邮箱 ,2025年05期
  • 【分类号】R563.9
  • 【下载频次】222
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