【摘要】 报告使用高通量测序技术诊断播散性带状疱疹1例。患者女，74岁，因腹痛腹胀1周就诊。患者2个月前确诊为抗中性粒细胞胞浆抗体(ANCA)相关性血管炎，予以免疫抑制治疗。1周前出现不明原因腹痛，入院后予以多种治疗后腹痛症状未见改善，送检腹水病原微生物DNA测序提示水痘带状疱疹病毒感染，2 d后患者左下肢出现条带状簇集性血疱伴疼痛。诊断：播散性带状疱疹。经积极治疗后效果不佳，患者未进一步治疗，目前已失访。更多还原

【Abstract】 We report a case of disseminated herpes zoster diagnosed by high-throughput sequencing. A 74-year-old female presented with a one-week history of abdominal pain and distension. Two months ago, she was diagnosed with ANCA-associated vasculitis and received immunosuppressive therapy. One week ago, she developed unexplained abdominal pain. Pathogen DNA sequencing of ascitic fluid indicated varicella-zoster virus infection. Two days later, the patient developed clustered hemorrhagic blisters with pain on her left lower limb. The patient was diagnosed with disseminated herpes zoster. Despite active treatment, the therapeutic response was unsatisfactory. The patient did not pursue further treatment and is currently lost to follow-up.更多还原