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慢性阻塞性肺疾病患者吸入制剂用药依从性影响因素和改善措施的研究进展

Research progress on influencing factors and improvement measures of inhalation medication compliance in patients with chronic obstructive pulmonary disease

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【作者】 官梦霞姜黎刘天虎颜晓燕李波

【Author】 GUAN Mengxia;JIANG Li;LIU Tianhu;YAN Xiaoyan;LI Bo;Chengdu Medical College;The Third Affiliated Hospital of Chengdu Medical College, Chengdu Pidu District People’s Hospital, Department of Clinical Pharmacy/Drug Clinical Trial Management Center;

【通讯作者】 颜晓燕;李波;

【机构】 成都医学院成都医学院第三附属医院,成都市郫都区人民医院药学部/药物临床试验管理中心

【摘要】 慢性阻塞性肺疾病(COPD)是一种以持续呼吸道症状和气流受限为特征的异质性肺部疾病。我国有近1亿的COPD患者,该疾病的死亡率较高。吸入制剂作为COPD治疗的一线选择,具有安全性高、起效快速及携带方便的优势,适用于COPD的长期治疗。尽管吸入制剂治疗COPD的效果显著,但在提升患者用药依从性方面仍面临重大挑战。现通过系统梳理COPD患者吸入制剂用药依从性影响因素和改善措施,为优化COPD的疾病管理提供参考依据。

【Abstract】 Chronic obstructive pulmonary disease(COPD) is a heterogeneous lung disease characterized by persistent respiratory symptoms and airflow limitation. It affects nearly 100 million patients in China and has a high mortality rate worldwide. As a first-line choice for the treatment of COPD, inhalation preparations have the advantages of high safety, rapid onset and portability, and are especially suitable for long-term treatment. Despite the significant effect of inhalation therapy, substantial challenges remain in enhancing patients’ medication compliance. Based on the guidelines and existing literature, this paper systematically sorts out the main influencing factors and improvement measures of inhalation medication compliance in COPD patients, aiming to provide a reference for optimizing COPD disease management.

【基金】 成都市医学科研课题(编号2024203);成都医学院研究生科研创新基金项目(编号YCX2024-03-13);成都医学院科技基金资助科研项目(编号CYSYB20-09);中国药学会全国医药信息网科普研究项目(编号CMEI2022KPYJ00271)
  • 【文献出处】 中国临床药学杂志 ,Chinese Journal of Clinical Pharmacy , 编辑部邮箱 ,2025年11期
  • 【分类号】R563.9
  • 【下载频次】157
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