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长期服用胺碘酮致肝脏胺碘酮沉积一例

Liver deposition of amiodarone after long-term use: a case report

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【作者】 周月俎明于金玉刘维

【Author】 ZHOU Yue;ZU Ming;YU Jinyu;LIU Wei;Department of Pharmacy, Peking University Third Hospital;Department of Pharmacy, China-Japan Friendship Hospital;Department of Gastroenterology, Peking University Third Hospital;Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital;Institute for Drug Evaluation, Peking University Health Science Center;

【通讯作者】 刘维;

【机构】 北京大学第三医院药学部中日友好医院药学部北京大学第三医院消化科北京大学第三医院肿瘤化疗与放射病科北京大学医学部药物评价中心

【摘要】 本文报道1例心房颤动患者使用盐酸胺碘酮片3年后出现肝脏胺碘酮沉积、肝脏脂肪变性,并结合文献资料对药物性肝损伤的发生和治疗过程进行详细分析梳理,以期为医师和药师对胺碘酮引起肝脏胺碘酮沉积、肝脏脂肪变性等不良反应进行鉴别、诊断、治疗提供参考。

【Abstract】 This article reports a case of atrial fibrillation in a patient who developed hepatic amiodarone deposition and hepatic steatosis after using amiodarone hydrochloride tablets for 3 years. The occurrence and treatment process of druginduced liver injury were analyzed and summarized in detail based on literature data in order to provide reference for physicians and pharmacists to distinguish, diagnose, and treat adverse reactions such as hepatic amiodarone deposition and hepatic steatosis caused by amiodarone.

【关键词】 胺碘酮肝脏沉积肝脏脂肪变性
【Key words】 amiodaroneliver depositionhepatic steatosis
  • 【文献出处】 临床药物治疗杂志 ,Clinical Medication Journal , 编辑部邮箱 ,2025年06期
  • 【分类号】R969
  • 【下载频次】30
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