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佳木斯市体检人群高尿酸血症流行状况及危险因素分析

Analysis of the prevalence and risk factors of hyperuricemia in the physical examination population in Jiamusi city

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【作者】 王博; 隋小芳; 魏金枫; 王琳琳; 伦雪琪; 王晓园; 邱洪斌;

【Author】 WANG Bo;SUI Xiaofang;WEI Jinfeng;WANG Linlin;LUN Xueqi;WANG Xiaoyuan;QIU Hongbin;Department of Epidemiology and Health Statistics, School of Public Health, Jiamusi University;Department of Geriatrics, The First Affiliated Hospital of Jiamusi University;Department of Health Management and Physical Examination Center, The First Affiliated Hospital of Jiamusi University;

【通讯作者】 邱洪斌;

【机构】 佳木斯大学公共卫生学院流行病与卫生统计学教研室; 佳木斯大学附属第一医院老年病科; 佳木斯大学附属第一医院健康管理体检中心;

【摘要】 目的:分析佳木斯市体检人群高尿酸血症(hyperuricemia, HUA)流行状况及危险因素,为制定HUA的预防策略提供参考。方法:选取2023年12月至2024年1月在佳木斯大学附属第一医院健康管理体检中心体检的人群为研究对象,采用多因素Logistic回归分析HUA的危险因素。结果:共纳入864例研究对象,男481例(55.67%),女383例(44.33%),发现高尿酸血症患者239例,患病率为27.66%。HUA组球蛋白、尿素氮、肌酐、血钙均高于非HUA组,高密度脂蛋白胆固醇低于非HUA组,差异均有统计学意义(P<0.05)。结论:年龄(30~39岁、40~49岁)、男性、肥胖、球蛋白、尿素氮、血钙是HUA的危险因素,高密度脂蛋白胆固醇是HUA的保护因素。

【Abstract】 Objective: To analyze the prevalence and risk factors of hyperuricemia(HUA) in the physical examination population in Jiamusi City and provide references for formulating prevention strategies for HUA. Methods: The physical examination population from the Health Management and Physical Examination Center of the First Affiliated Hospital of Jiamusi University from December 2023 to January 2024 was selected as the study subjects. Multivariate logistic regression was used to analyze the risk factors for HUA. Results: A total of 864 subjects were included, with 481 males(55.67%) and 383 females(44.33%). A total of 239 cases of HUA were identified, with a prevalence rate of 27.66%. The HUA group had higher levels of globulin, blood urea nitrogen, creatinine and serum calcium compared to the non-HUA group, while the high-density lipoprotein cholesterol level was lower than that of the non-HUA group, with statistically significant differences(P<0.05). Conclusion: Age(30~39 years old, 40~49 years old), male gender, obesity, globulin, blood urea nitrogen and serum calcium are risk factors for HUA, while high-density lipoprotein cholesterol is a protective factor.

【基金】 黑龙江省自然科学基金重点项目,编号:ZD2022H006;黑龙江省省属高等学校基本科研业务费科研项目,编号:2022-KYYWF-0651;黑龙江省痛风研究重点实验室开放课题,编号:TFYJ202301
  • 【文献出处】 黑龙江医药科学 ,Heilongjiang Medicine and Pharmacy , 编辑部邮箱 ,2025年07期
  • 【分类号】R589.7
  • 【下载频次】34
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