【摘要】 药学专业基础化学教学是培育创新药物研发人才的关键环节。传统教学存在若干痛点，研究以“整合药学”理念为引领，探索教学改革路径：重构教学内容，实现化学原理与药物研发实践的深度融合；创新教学模式，通过PBL、虚拟仿真及校企协同的顶石项目强化探究能力；整合实验教学体系，依托动态分子模拟系统与开放共享平台提升自主设计能力；建立过程性与能力导向的评价机制。实践表明，该模式有效提升了学生的创新思维与实践能力，为药学教育适应新医科需求提供了理论支撑。更多还原

【Abstract】 Basic chemistry teaching for pharmacy majors is a key link in cultivating talents for innovative drug research and development. There are several pain points in traditional teaching. Guided by the concept of "integrated pharmacy",this study explores the path of teaching reform:reconstructing teaching content to achieve in-depth integration of chemical principles and drug research and development practices; innovating teaching models to strengthen inquiry ability through PBL,virtual simulation,and school-enterprise collaborative capstone projects; integrating experimental teaching systems to improve independent design ability relying on dynamic molecular simulation systems and open sharing platforms; establishing a process-oriented and ability-oriented evaluation mechanism. Practice has shown that this model effectively improves students’ innovative thinking and practical ability,providing theoretical support for pharmacy education to meet the needs of the new medical science.更多还原