【摘要】 目的:分析鉴定角花胡颓子水提取液中的化学成分。方法:采用液质联用分析检测，获取高分辨质谱图中正负离子流信号及紫外吸收峰信号对应的各化合物的精确分子量、一级和二级质谱碎片信息；对测定出的数据信息用文献数据库及Compound discovery 2.0软件在线进行化合物库搜索比对，鉴定出角花胡颓子水提取液中存在的化学成分。结果:首次鉴定和报道了角花胡颓子中的23个化合物，包含2个黄酮苷和21个含氮化合物，对含量相对较高的化合物进行了结构解析，发现其中的两个黄酮苷类化合物的紫外吸收较强，可以作为该药材的代表性化合物。结论:本研究对角花胡颓子水提取液进行了成分及其结构分析，主要化学成分为生物碱类和黄酮苷，分析结果可为角花胡颓子药材及其产品的质量标准提升提供参考。更多还原

【Abstract】 Objective:To analyze and identify the chemical components in the water extract of Elaeagnus gonyanthes Benth.. Methods: High performance liquid chromatography-tandem mass spectrometry was used to obtain the accurate molecular weight, primary and secondary mass spectrometric fragment information of each compound corresponding to the positive and negative ion current signals and ultraviolet absorption peak signals in the high resolution mass spectrum, the determined data information was searched and compared with the online compound library using the literature database and the Compound Discovery 2.0 software provided by the instrument supplier, and some of the main chemical substances present in the water extract of Elaeagnus gonyanthes Benth. were identified. Results: 23 compounds in Elaeagnus gonyanthes Benth. were identified and reported for the first time, including 2 flavonoid glycosides and 21 nitrogen-containing compounds. Structural analyses were done on the compounds with high absorption intensities.Two of the flavonoid glycosides had high UV absorption intensity and can be used as representative compounds of the herb. Conclusion:This study conducted a composition and structural analysis of the chemical substances in the aqueous extract of Elaeagnus gonyanthes Benth., whose main components are alkaloids and flavonoid glycosides. The analysis results could provide a reference for the improvement of the quality standard of Elaeagnus gonyanthes Benth. and its products.更多还原