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重症急性胰腺炎并发胰腺感染的危险因素分析

Analysis of risk factors for severe acute pancreatitis complicated with pancreatic infection

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【作者】 张菊梅; 张娅; 吴婧; 王安丽; 杨卫文;

【Author】 ZHANG Jumei;ZHANG Ya;WU Jing;WANG Anli;YANG Weiwen;Department of Gastroenterology, the Second People’s Hospital of Guiyang;

【通讯作者】 杨卫文;

【机构】 贵阳市第二人民医院消化内科;

【摘要】 目的 分析重症急性胰腺炎(SAP)并发胰腺感染的危险因素。方法 回顾性分析2023年5月—2024年5月贵阳市第二人民医院收治的120例SAP患者的临床资料,根据入院后是否并发胰腺感染,分为感染组(n=51)和非感染组(n=69)。收集患者的各项临床资料,并采用多因素Logistic回归分析对SAP并发胰腺感染的危险因素进行分析。结果 单因素分析结果显示,感染组多器官功能衰竭发生率高于非感染组,血钙和血清蛋白水平低于非感染组,差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示,多器官功能衰竭、血钙水平降低及血清蛋白水平降低是SAP并发胰腺感染的独立危险因素(P<0.05)。结论 SAP并发胰腺感染的危险因素包括多器官功能衰竭、血钙水平降低及血清蛋白水平降低。

【Abstract】 Objective To analyze the risk factors of severe acute pancreatitis(SAP) complicated with pancreatic infection.Methods The clinical data of 120 patients with SAP admitted to the Second People’s Hospital of Guiyang from May 2023 to May 2024 were retrospectively analyzed. According to whether they were complicated with pancreatic infection after admission, they were divided into infection group(n = 51) and non-infection group(n = 69). The clinical data of the patients were collected, and the risk factors of SAP complicated with pancreatic infection were analyzed by multivariate Logistic regression analysis. Results Univariate analysis showed that the incidence of multiple organ failure in the infection group was higher than that in the non-infection group,and the levels of serum calcium and serum protein were lower than those in the non-infection group(P < 0.05). Multivariate Logistic regression analysis showed that multiple organ failure, decreased serum calcium level and decreased serum protein level were independent risk factors for SAP complicated with pancreatic infection(P < 0.05). Conclusions The risk factors of SAP complicated with pancreatic infection include multiple organ failure, decreased serum calcium level and decreased serum protein level.

【基金】 贵阳市卫生健康局科学技术计划项目(【2022】筑卫健科技合同字第009号)
  • 【文献出处】 医药前沿 ,Journal of Frontiers of Medicine , 编辑部邮箱 ,2025年19期
  • 【分类号】R576
  • 【下载频次】74
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