【摘要】 抑郁症的病因及发病机制较为复杂，不同的患者对治疗的反应不一。与特定心理应激相关的抑郁发作患者的治疗效果总体不理想，其原因和机制尚不明确。近年来，神经免疫学和炎症因子方面的研究为与特定心理应激相关的抑郁发作患者的临床诊断与治疗提供了新思路。现归纳总结心理应激、抑郁症与炎症因子三者的关联，旨在揭示与特定心理应激相关的抑郁发作潜在的发病机制。更多还原

【Abstract】 The etiology and pathogenesis of depressive disorder are complex, and different patients respond differently to treatment. Treatment outcomes for patients with depressive episodes associated with specific psychological stress are generally suboptimal, and the causes and mechanisms for this are still unclear. The research in neuroimmunology and inflammatory factors provides new ideas for the clinical diagnosis and treatment of patients with depressive episodes associated with specific psychological stress. This paper summarizes the association between psychological stress, depressive disorder and inflammatory factors with the aim of revealing the potential pathogenesis of depressive episodes associated with specific psychological stress.更多还原