【摘要】 糖尿病肾脏病（DKD）是终末期肾病的重要原因。肾间质纤维化（RIF）是DKD发展至终末期肾病的必经阶段，其发病机制和病机演变过程十分复杂。本文从中西医角度阐述“虚气流滞”与DKD-RIF的关系及DKD-RIF的病机特点，以“虚气”为本，“流滞”为标，以此确立了补虚通滞的治疗总则。研究表明中药能通过遣方用药治疗DKD-RIF，对延缓甚至阻断DKD向肾纤维化进展具有重要意义，可为DKD-RIF防治提供新视角。更多还原

【Abstract】 Diabetic kidney disease(DKD)is an important cause of end-stage renal disease. Renal interstitial fibrosis(RIF)is a necessary stage for DKD to develop into end-stage renal disease,and its pathogenesis is complex. This paper expounds the relationship between“vacuity airflow stagnation”and DKD-RIF from the perspective of traditional Chinese and Western medicine, and the pathogenesis characteristics of DKD-RIF, in which“deficient-Qi”is the ben, and“stagnation”is the biao,and the general treatment principle of tonifying deficiency and clearing stagnation is established. Studies have shown that traditional Chinese medicine treats DKD-RIF through prescription medication, which is of great significance for delaying or even blocking the progression of DKD to renal fibrosis, and can provide a new perspective for the prevention and treatment of DKD-RIF.更多还原